123-90-0, Thiomorpholine is a Thiomorpholine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 11 Synthesis of 1-amino-3-(1,1-dioxo-lambda6-thiomorpholin-4-yl)-propan-2-ol To the solution of thiomorpholine (5.0 g, 48.7 mmol) in HOCH3 (200 mL) was added the solution of oxone (36.0 g, 58.5 mmol) in H2O (100 mL). The mixture was well stirred at 40¡ã C. for 48 h and then cooled to 0¡ã C. Aqueous NaOH was added dropwise to adjust pH=12. Solid was filtered out and washed with HOCH3 (3*40 mL). The combined liquid was condensed and purified by flash chromatograph on silica gel (CHCl3/CH30H/NH3.H2O=3/1/0.1-2/1/0.1) to give thiomorpholine 1,1-dioxide (6.2 g)in 93percent yield. 1H NMR (DMSO-d6) delta 2.97 (m, 4H), 3.07 (m, 4H), 3.42 (brs, 1H), MS (m/z) 136 (M+1).
The synthetic route of 123-90-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SUGEN, INC.; US2003/92917; (2003); A1;,
Thiomorpholine – Wikipedia
Thiomorpholine | C4H9NS – PubChem