Thiomorpholine 1,1-dioxide, cas is 39093-93-1, it is a common heterocyclic compound, the Thiomorpholine compound, its synthesis route is as follows.,39093-93-1
1,3-dibromobenzene (1.6g, 6.81mmol),thiomorpholine dioxide (300mg, 2.22mmol) BINAP (300mg, 0.48mmol), cesium carbonate (2.5g, 23.67mmol) and palladiumacetate (150mg) were dissolved in 10mL dry toluene in a 50mL single-neck flask. The reaction solution washeated to 90¡ãC under argon atmosphere and stirred for 18 hours. After completion of the reaction, the reaction solutionwas filtered, the filtrate was evaporated to dryness under reduced pressure, and the residue was purified by columnchromatography to give 90mg product, which was directly used in the next step.
39093-93-1 is used more and more widely, we look forward to future research findings about Thiomorpholine 1,1-dioxide
Reference£º
Patent; Shanghai Pharmaceuticals Holding Co., Ltd.; XIA, Guangxin; LI, Di; ZUO, Hongjian; WU, Guangsheng; DUAN, Lingjun; ZHANG, Jing; MAO, Yu; LIU, Yanjun; (152 pag.)EP3424928; (2019); A1;,
Thiomorpholine – Wikipedia
Thiomorpholine | C4H9NS – PubChem