Electric Literature of 102-06-7, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 102-06-7, Name is 1,3-Diphenylguanidine, SMILES is N=C(NC1=CC=CC=C1)NC2=CC=CC=C2, belongs to thiomorpholine compound. In a article, author is Battula, Kumaraswamy, introduce new discover of the category.
Synthesis and antimicrobial evaluation of some novel thiomorpholine derived 1,4-disubstituted 1,2,3-triazoles
A convenient synthesis of novel 1,4-disubstituted 1,2,3-triazoles (4a-j and 5a-j) is reported via copper(I)-catalyzed one pot [3+ 2] cycloaddition of various alkyl halides, sodium azide with 4-(prop-2-yn-1-yl) thiomorpholine and 4-(prop-2-yn-1-yl) thiomorpholine 1,1-dioxide. All the synthesized compounds were investigated for their antimicrobial activity. Compounds 4a, 4b, 4c, 4g, 5a and 5j against Staphylococcus epidermidis, 4a, 5a and 5d against Pseudomonas aeruginosa, 4a, 4b and 4g against Klebsiella pneumoniae, 4b, 5a and 5d against S. aureus and 5b, 5e and 5j against Bacillus subtilis showed excellent antibacterial activity compared to the standard drugs penicillin and streptomycin. Compounds 4c, 4e, 4f, 4j, 5c, 5d, 5g and 5j registered moderate antifungal activity as compared with the standard drug amphotericin B.
Electric Literature of 102-06-7, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 102-06-7.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem