Application of 123843-67-4, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 123843-67-4, Name is 4-Bromo-2,6-difluorobenzonitrile, SMILES is N#CC1=C(F)C=C(Br)C=C1F, belongs to thiomorpholine compound. In a article, author is Lima, LM, introduce new discover of the category.
Synthesis and anti-inflammatory activity of phthalimide derivatives, designed as new thalidomide analogues
This paper describes the synthesis and anti-inflammatory activity of new N-phenyl-phthalimide sulfonamides (3a-e) and the isosters N-phenyl-phthalimide amides (4a-e), designed as hybrids of thalidomide (1) and aryl sulfonamide phosphodiesterase inhibitor (2), In these series, compound 3e (LASSBio 468). having a sulfonyl-thiomorpholine moiety, showed potent inhibitory activity on LPS-induced neutrophil recruitment with ED50 = 2.5 mg kg(-1), which was correlated with its inhibitory effect on TNF-alpha level. (C) 2002 Elsevier Science Ltd. All rights reserved.
Application of 123843-67-4, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 123843-67-4 is helpful to your research.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem