In an article, author is Candela-Lena, Jose I., once mentioned the application of 2579-22-8, COA of Formula: C9H6O, Name is 3-Phenylpropiolaldehyde, molecular formula is C9H6O, molecular weight is 130.14, MDL number is MFCD00006995, category is thiomorpholine. Now introduce a scientific discovery about this category.
Asymmetric synthesis of alpha-mercapto-beta-amino acid derivatives: application to the synthesis of polysubstituted thiomorpholines
Tandem conjugate addition of homochiral lithium N-benzyl-N-(alpha-methyl-p-methoxybenzyl)amide to tert-butyl cinnamate and enolate trapping with (TsSBu)-Bu-t proceeds with high diastercoselectivity to give a homochiral anti-alpha-tert-butylthio-beta-amino ester. Stepwise deprotection gives the corresponding free alpha-tert-butylthio-beta-amino acid without epimerisation. Tandem conjugate addition of homochiral lithium N-allyl-N-(alpha-methylbenzyl)amide to tert-butyl cinnamate and enolate trapping with TsS’Bu followed by conversion of the S-tert-butyl group to a disulphide, and reduction with Lalancette’s reagent generates polysubstituted thiomorpholine derivatives. (c) 2006 Elsevier Ltd. All rights reserved.
If you are interested in 2579-22-8, you can contact me at any time and look forward to more communication. COA of Formula: C9H6O.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem