Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 611-19-8, Name is 1-Chloro-2-(chloromethyl)benzene, SMILES is ClCC1=C(C=CC=C1)Cl, belongs to thiomorpholine compound. In a document, author is Krasheninina, Olga A., introduce the new discover, Recommanded Product: 611-19-8.
Postsynthetic On-Column 2 ‘ Functionalization of RNA by Convenient Versatile Method
We report a universal straightforward strategy for the chemical synthesis of modified oligoribonucleotides containing functional groups of different structures at the 2 ‘ position of ribose. The on-column synthetic concept is based on the incorporation of two types of commercial nucleotide phosphoramidites containing orthogonal 2 ‘-O-protecting groups, namely 2 ‘-O-thiomorpholine-carbothioate (TC, as permanent) and 2 ‘-O-tert-butyl(dimethyl)silyl (tBDMS, as temporary), to RNA during solid-phase synthesis. Subsequently, the support-bound RNA undergoes selective deprotection and follows postsynthetic 2 ‘ functionalization of the naked hydroxyl group. This convenient method to tailor RNA, utilizing the advantages of solid phase approaches, gives an opportunity to introduce site-specifically a wide range of linkers and functional groups. By this strategy, a series of RNAs containing diverse 2 ‘ functionalities were synthesized and studied with respect to their physicochemical properties.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 611-19-8 is helpful to your research. Recommanded Product: 611-19-8.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem