Chemistry is an experimental science, HPLC of Formula: C7H8O2, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 90-05-1, Name is Guaiacol, molecular formula is C7H8O2, belongs to thiomorpholine compound. In a document, author is Yamakuma, Michiko.
1-HYDROXYETHYLHALENAQUINONE: A NEW PROTEASOME INHIBITOR FROM THE MARINE SPONGE XESTOSPONGIA SP.
A new halenaquinone derivative, 1-hydroxyethylhalenaquinone (1), was isolated from the marine sponge Xestospongia sp. as a proteasome inhibitor together with three known compounds, halenaquinone (2) and 3-ketoadociaquinones A (3) and B (4). 1-Hydroxyethylhalenaquinone (1) was the first halenaquinone derivative containing an alkyl group at the keto-furan C-1 position. Compounds 1 and 2 inhibited the chymotrypsin-like activity of the proteasome with IC50 values of 0.19 and 0.63 mu M, respectively, whereas 3 or 4, each containing a thiomorpholine 1,1-dioxide moiety, scarcely inhibited its activity, even at a concentration of 5 mu M.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 90-05-1, in my other articles. HPLC of Formula: C7H8O2.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem