Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 1075-49-6, Name is 4-Vinylbenzoic acid, molecular formula is C9H8O2. In an article, author is Yamakuma, Michiko,once mentioned of 1075-49-6, Safety of 4-Vinylbenzoic acid.
1-HYDROXYETHYLHALENAQUINONE: A NEW PROTEASOME INHIBITOR FROM THE MARINE SPONGE XESTOSPONGIA SP.
A new halenaquinone derivative, 1-hydroxyethylhalenaquinone (1), was isolated from the marine sponge Xestospongia sp. as a proteasome inhibitor together with three known compounds, halenaquinone (2) and 3-ketoadociaquinones A (3) and B (4). 1-Hydroxyethylhalenaquinone (1) was the first halenaquinone derivative containing an alkyl group at the keto-furan C-1 position. Compounds 1 and 2 inhibited the chymotrypsin-like activity of the proteasome with IC50 values of 0.19 and 0.63 mu M, respectively, whereas 3 or 4, each containing a thiomorpholine 1,1-dioxide moiety, scarcely inhibited its activity, even at a concentration of 5 mu M.
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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem