As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. In an article, author is Fathalla, Magda F., once mentioned the application of 64-10-8, Name is 1-Phenylurea, molecular formula is C7H8N2O, molecular weight is 136.1512, MDL number is MFCD00007944, category is thiomorpholine. Now introduce a scientific discovery about this category, Computed Properties of C7H8N2O.
Kinetics of the nucleophilic substitution reactions of methyl 2,4-dichloro-3,5-dinitrobenzoate with piperidine, piperazine, morpholine and thiomorpholine in methanol and benzene
The kinetic of the nucleophilic substitution of methyl 2,4-dichloro-3,5-dinitrobenzoate with piperidine, piperazine, morpholine and thiomorpholine in methanol and benzene were determined spectrophotometrically at different amine concentrations and at temperatures ranging from 25 to 45 degrees C. The second order rate constants and the thermodynamic parameters show that the reactions are not amine catalysed and are greatly dependent of the nature of solvent and amine. UV, IR, H-1 NMR, and elemental analysis are used to prove the aminodechlorination at C-2.
Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms.If you are interested in 64-10-8, you can contact me at any time and look forward to more communication. Computed Properties of C7H8N2O.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem