The main research directions are chemical synthesis, new energy materials, nano-ceramics, nano-hybrid composite materials, preparation and modification of special coatings, and research on the structure and performance of functional materials. 90-05-1, Name is Guaiacol, molecular formurla is C7H8O2. In a document, author is Yamakuma, Michiko, introducing its new discovery. Safety of Guaiacol.
1-HYDROXYETHYLHALENAQUINONE: A NEW PROTEASOME INHIBITOR FROM THE MARINE SPONGE XESTOSPONGIA SP.
A new halenaquinone derivative, 1-hydroxyethylhalenaquinone (1), was isolated from the marine sponge Xestospongia sp. as a proteasome inhibitor together with three known compounds, halenaquinone (2) and 3-ketoadociaquinones A (3) and B (4). 1-Hydroxyethylhalenaquinone (1) was the first halenaquinone derivative containing an alkyl group at the keto-furan C-1 position. Compounds 1 and 2 inhibited the chymotrypsin-like activity of the proteasome with IC50 values of 0.19 and 0.63 mu M, respectively, whereas 3 or 4, each containing a thiomorpholine 1,1-dioxide moiety, scarcely inhibited its activity, even at a concentration of 5 mu M.
Safety of Guaiacol, In conclusion, we affirm that quantitative kinetic descriptions of catalytic behavior continue to serve as an indispensable tool to navigate research efforts.you can also check out more blogs about 90-05-1.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem