The main research directions are chemical synthesis, new energy materials, nano-ceramics, nano-hybrid composite materials, preparation and modification of special coatings, and research on the structure and performance of functional materials. 99-61-6, Name is 3-Nitrobenzaldehyde, molecular formurla is C7H5NO3. In a document, author is Renaud, T, introducing its new discovery. Formula: https://www.ambeed.com/products/99-61-6.html.
Synthesis of new quinoxaline derivatives by reductive cyclization of various 1-(2-nitrophenyl)-2-cyanoamines
The electrochemical cyanation of various six-membered N-(2-nitrophenyl) heterocyclic amines, including piperidine, morpholine, thiomorpholine, and N-Boc-protected piperazine derivatives, was investigated. The expected cyanoamines 5 were obtained in good yields and subjected to catalytic hydrogenation to afford the corresponding cyclic amidine N-oxides 6. The reductive cyclization proceeded through the formation of a hydroxylamine, which cyclized onto the cyano moiety. The stereoselectivity of the cyclization reaction was studied for the cases both of trans-5f, in which the substituent was axial and the 4-methyl substituent equatorial, and of cis-5f, in which both the 2-cyano and the substituents were equatorial. The expected tetrahydroquinoxalines 3 were conveniently prepared in a following step by the catalytic hydrogenation of cyclic amidines 6 in the presence of Pearlman’s catalyst at five atmospheres of hydrogen pressure.
Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.Welcome to check out more blogs about 99-61-6, in my other articles. Formula: https://www.ambeed.com/products/99-61-6.html.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem