Discovery of 4,4-Methylenebis(2,6-diethylaniline)

The design and synthesis of related molecules that are more effective, more selective, and less toxic than aspirin are important objectives of biomedical research. I hope my blog about 13680-35-8 is helpful to your research. Electric Literature of 13680-35-8.

Electric Literature of 13680-35-8, Chemistry, like all the natural sciences, begins with the direct observation of nature— in this case, of matter. 13680-35-8, Name is 4,4-Methylenebis(2,6-diethylaniline), SMILES is NC1=C(CC)C=C(CC2=CC(CC)=C(C(CC)=C2)N)C=C1CC, molecular formula is C21H30N2, belongs to thiomorpholine compound. In an article, author is El-Faham, Ayman, introduce new discover of the category.

Morpholine-based immonium and halogenoamidinium salts as coupling reagents in peptide synthesis

Here we describe a new family of N-form immonium-type coupling reagents that differ in their carbocation skeleton structure. The N-methylpiperazine derivative failed to form immonium salts, while the thiomorpholine derivative did not give better results than the coupling reagents currently used. The presence of the morpholine had a marked influence on the solubility and stability as well as the reactivity of the reagent. Finally, the fluoroamidinium salt performed extremely well in the presence of only 1 equiv of base, thereby confirming the effect of the proton acceptor in the reaction.

The design and synthesis of related molecules that are more effective, more selective, and less toxic than aspirin are important objectives of biomedical research. I hope my blog about 13680-35-8 is helpful to your research. Electric Literature of 13680-35-8.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem