As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. In an article, author is Babu, K. Sudhakar, once mentioned the application of 131-56-6, Name is (2,4-Dihydroxyphenyl)(phenyl)methanone, molecular formula is C13H10O3, molecular weight is 214.22, MDL number is MFCD00002277, category is thiomorpholine. Now introduce a scientific discovery about this category, Name: (2,4-Dihydroxyphenyl)(phenyl)methanone.
Objective: In search of new potential antimicrobial agents, the aim of the present study was to synthesize the series of Quinazoline analogs by a simple and accessible approach and evaluate for their antimicrobial activity. Methods: Synthetic methodology involves the reaction of an anthranilic acid (1) with urea toget -2,4 di hydroxyl quinazoline (2) intermediate, which were further treated with POCl3 to get 2,4 di chloro quinazoline (3) derivative. Next 2,4 di chloro quinazoline (3) reacts with hydrazine hydrate in methanol for 4 hrs to get compounds, which further reacts with different carboxylic acids in POCl3 a series of novel fused 1,2,4 triazole derivatives, which were reacts with 4-thiomorpholinoaniline (7) in acetic acid to give target compounds (8a-k) in good yields. Results: The structures of the synthesized compounds were provided by spectral analysis, and the Synthesised compounds were tested for their antimicrobial activity against different fungi and bacteria species in vitro. Conclusion: The results of the study reveal that the new compounds possess promising antimicrobial activities.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. These may comprise an expansion of the substrate scope from aromatic and heteroaromatic compounds to other hydrocarbons. 131-56-6, you can contact me at any time and look forward to more communication. Name: (2,4-Dihydroxyphenyl)(phenyl)methanone.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem