New Advances in Chemical Research, May 2021. The prevalence of solvent effects has motivated developing quantitative kinetic, and theoretical assessments of solvent structures and their interactions with reaction intermediates. In an article, author is Amezcua, CA, once mentioned the application of 13680-35-8, Name is 4,4-Methylenebis(2,6-diethylaniline), molecular formula is C21H30N2, molecular weight is 310.4763, MDL number is MFCD00071552, category is thiomorpholine. Now introduce a scientific discovery about this category, Application In Synthesis of 4,4-Methylenebis(2,6-diethylaniline).
Thiomorpholine-N-borane was synthesized via amine displacement of BH3 from tetrahydrofuran-borane which had been prepared from NaBH4 and BF3. Et2O in tetrahydrofuran. Acid-catalyzed hydrolysis occurs only slightly faster than for morpholine-borane, the difference being attributed to a small difference in the electronic inductive effects of sulfur and oxygen in the 4-position of the respective adducts. Reaction with NaOCl exhibits a stoichiometric [OCl-]:[S(CH2)(4)NHBH3] ratio of 5:1. This is attributed to consumption of 3 mol of hypochlorite for the oxidation of hydridic hydrogen in BH3, one for the chlorination of nitrogen and another in attack at sulfur presumably resulting in sulfoxide formation. At pH 9.1-10.4, the initial reaction of hypochlorite with thiomorpholine-borane is several times faster than with morpholine-borane and, unlike the reaction with morpholine-borane, relatively insensitive to pH. Whereas hypochlorite oxidation of morpholine-borane has been proposed to occur primarily through reaction with HOCl, it is speculated that thiomorpholine-borane is also susceptible to attack by hypochlorite ion. (C) 1999 Elsevier Science S.A. All rights reserved.
I am very proud of our efforts over the past few months and hope to 13680-35-8 help many people in the next few years. Application In Synthesis of 4,4-Methylenebis(2,6-diethylaniline).
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem