Synthetic Route of 115-86-6, New discoveries in chemical research and development in 2021.Chemistry can be defined as the study of matter and the changes it undergoes. 115-86-6, Name is Triphenyl phosphate, SMILES is O=P(OC1=CC=CC=C1)(OC2=CC=CC=C2)OC3=CC=CC=C3, belongs to thiomorpholine compound. In a article, author is Sreerama, Rakesh, introduce new discover of the category.
A one-pot procedure for the synthesis of novel 1,2,3-triazole derivatives (5a-5l) in good yields (63 to 77%) using different sulfonic acids and 4-(prop-2-yn-1-yl)thiomorpholine 1,1-dioxide through the in situ generated sulfonyl azides was developed. The structures of the newly synthesized compounds were confirmed by H-1 NMR, C-13 NMR, mass spectrometry, and elemental analysis. The newly synthesized compounds were screened for in vitro antibacterial activity and free radical scavenging activity in terms of hydrogen donating or radical scavenging ability by the DPPH method. Among all, the compound N-(4-((4-((1,1-dioxidothiomorpholino) methyl)-1H-1,2,3-triazol-1-yl)sulfonyl)phenyl) acetamide (5l) was found to exhibit potent activity as compared to the standard drugs.
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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem