Our Top Choice Compound: 766-98-3

The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.you can check my other blog about 766-98-3, you can contact me at any time and look forward to more communication. Related Products of 766-98-3.

Related Products of 766-98-3, New discoveries in chemical research and development in 2021.The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 766-98-3, Name is 1-Ethynyl-4-fluorobenzene, SMILES is FC1=CC=C(C#C)C=C1, molecular formula is C8H5F, belongs to thiomorpholine compound. In an article, author is Marvadi, Sandeep Kumar, introduce new discover of the category.

This study describes synthesis and evaluation of novel 5-Chloro-2-thiophenyl-1,2,3-triazolylmethyldihydroquinolines 7a-o as dual inhibitors of Mycobacterium tuberculosis and influenza virus. Huisgen’s [ 3+ 2] dipolar cycloaddition of 6-(azidomethyl)-5-chloro-2-(thiophen-2-yl)-7,8-dihydroquinoline 5 with various alkynes 6a-o using sodium ascorbate and copper sulphate gave new dihydroquinoline-1,2,3-triazoles 7a-o in good to excellent yields. The new compounds were evaluated for in vitro antimycobacterial against M. tuberculosis H37Rv (Mtb) and antiviral activity against influenza virus A/Puerto Rico/8/34 (H1N1). Among the fifteen new analogs, compounds 7a (MIC: 3.12 mu g/mL), 7j and 7k (MIC: 6.25 mu g/mL) were identified as potent antitubercular agents. The virus-inhibiting activity of all the fifteen compounds was found to be moderate, and among them the compound 7l, bearing thiophene moiety appeared the most active with good selectivity index (IC50 = 19.5 mu g/mL; SI = 15). The results presented here will help developing newer dual inhibitors of tuberculosis and influenza virus.

The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.you can check my other blog about 766-98-3, you can contact me at any time and look forward to more communication. Related Products of 766-98-3.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem