Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process., Formula: https://www.ambeed.com/products/827-95-2.html, 827-95-2, Name is Sodium 3-nitrobenzoate, molecular formula is C7H4NNaO4, belongs to thiomorpholine compound. In a document, author is Kralova, Petra, introduce the new discover.
Herein, we report the stereoselective synthesis of trisubstituted benzoxazino[4,3-b]{1,2,5}thiadiazepinone 6,6-dioxides from polymer-supported Fmoc-Ser(tBu)-OH and Fmoc-Thr(tBu)-OH. After the solid-phase synthesis of N-alkylated-Nsulfonylated intermediates using various 2-nitrobenzenesulfonyl chlorides and bromoketones, the target compounds were obtained via trifluoroacetic acid (TFA)-mediated cleavage from the resin, followed by cyclization of the diazepinone scaffold. Except for the threonine-based intermediates, the inclusion of triethylsilane (TES) in the cleavage cocktail yielded a specific configuration of the newly formed C-3 chiral center. The final cyclization resulted in minor or no inversion of the C-12a stereocenter configuration.
The design and synthesis of related molecules that are more effective, more selective, and less toxic than aspirin are important objectives of biomedical research. You can also check out more blogs about 827-95-2. Formula: https://www.ambeed.com/products/827-95-2.html.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem