Application of 30379-55-6, New discoveries in chemical research and development in 2021.The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 30379-55-6, Name is 2-(Benzyloxy)acetic acid, SMILES is O=C(O)COCC1=CC=CC=C1, molecular formula is C9H10O3, belongs to thiomorpholine compound. In an article, author is Battula, Kumara Swamy, introduce new discover of the category.
In this report, we describe the synthesis and biological evaluation of a new series of (4-((1-(aryl)-1H-1,2,3-triazol-4-yl) methoxy) phenyl)(1,1-dioxidothiomorpholino) methanone derivatives (6a-6n). All the new derivatives were well analyzed by (HNMR)-H-1, (CNMR)-C-13, FTIR, mass spectral and elemental data. The synthesized compounds were screened for in vitro anticancer activity against three cancer cell lines (MCF-7, HeLa, and HEK293) and compared with standard drug cisplatin. Three (6b, 6g and 6i) out of fourteen derivatives exhibited potent anticancer activity against MCF-7, HeLa, and HEK293. Two ( 6b and 6g) potent hybrids were screened for in vivo studies against EAC bearing mice and found to possess potential anticancer activity.
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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem