Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process., Application of 620-23-5, 620-23-5, Name is 3-Tolualdehyde, molecular formula is C8H8O, belongs to thiomorpholine compound. In a document, author is Levin, JI, introduce the new discover.
A series of thiomorpholine sulfonamide hydroxamate TACE inhibitors, all bearing propargylic ether P1′ groups, was explored. In particular, compound 5h has excellent in vitro potency against isolated TACE enzyme and in cells, oral activity in a model of TNF-alpha production and a collagen-induced arthritis model, was selected as a clinical candidate for the treatment of RA. (C) 2005 Elsevier Ltd. All rights reserved.
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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem