Electric Literature of 81-64-1, New discoveries in chemical research and development in 2021.The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 81-64-1, Name is 1,4-Dihydroxyanthracene-9,10-dione, SMILES is O=C1C2=C(C=CC=C2)C(C3=C(O)C=CC(O)=C13)=O, molecular formula is C14H8O4, belongs to thiomorpholine compound. In an article, author is Tanokashira, Natsuki, introduce new discover of the category.
We isolated 16 new xestoquinone derivatives, including two trimers, six dimers, and four monomers with containing thiomorpholine 1,1-dioxide and pyrrolidine-2,4-diol moieties, from the marine sponge Petrosia alfiani and determined their structures including the absolute configurations using computational methods. They exhibited potent inhibitory activities against USP7 with 1050 values in the range of 0.13-2.0 mu M. (C) 2016 Elsevier Ltd. All rights reserved.
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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem