While the job of a research scientist varies, most chemistry careers in research are based in laboratories, where research is conducted by teams following scientific methods and standards., Category: thiomorpholine, 53499-40-4, Name is 2-(Benzhydryloxy)-N-methylethanamine hydrochloride, molecular formula is C16H20ClNO, belongs to thiomorpholine compound. In a document, author is Krishnaraj, Thulasiraman, introduce the new discover.
Treatment of 2-(2-oxo-2-arylethylthio)-N-(4H-1,2,4-triazol-3-yl)acetamides with paraformaldehyde in the presence of a base has led to a tandem chemoselective hydroxymethylation followed by cyclization yielding a set of novel 6-aroyl-4-(4H-triazol-3-yl)thiomorpholin-3-ones. The thiomorpholine ring has been found to have a boat like conformation in these compounds as evidenced by NOESY NMR spectrum. (C) 2011 Elsevier Ltd. All rights reserved.
The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.you can check my other blog about 53499-40-4, you can contact me at any time and look forward to more communication. Application In Synthesis of 2-(Benzhydryloxy)-N-methylethanamine hydrochloride.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem