Academic researchers, R&D teams, teachers, students, policy makers and the media all rely on us to share knowledge that is reliable, accurate and cutting-edge. In an article, author is Benharref, Ahmed, once mentioned the application of 455-14-1, Name is 4-(Trifluoromethyl)aniline, molecular formula is C7H6F3N, molecular weight is 161.1245, MDL number is MFCD00064396, category is thiomorpholine. Now introduce a scientific discovery about this category, Application In Synthesis of 4-(Trifluoromethyl)aniline.
The title compound, C19H29NO4S, was synthesised from 9 alpha-hydroxyparthenolide (9 alpha-hydroxy-4,8-dimethyl-12-methylene-3,14-dioxatricyclo[9.3.0.0(2,4)]tetradec-7-en-13-one), which was isolated from the chloroform extract of the aerial parts of the plant Anvillea radiata. The molecule is built up from two fused five-and ten-membered rings, with an additional epoxy ring system and a thiomorpholine group as a substituent. The ten-membered ring adopts an approximate chair-chair conformation, while the thiomorpholine ring displays a chair conformation and the five-membered ring has an envelope conformation, with the C atom closest to the hydroxy group forming the flap. An intramolecular O-H center dot center dot center dot N hydrogen bond closes an S(8) ring. The crystal structure features weak C-H center dot center dot center dot O hydrogen-bonding interactions, which link the molecules into [010] chains.
Application In Synthesis of 4-(Trifluoromethyl)aniline, You can get involved in discussing the latest developments in this exciting area about 455-14-1.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem