Healthcare careers for chemists are once again largely based in laboratories, although increasingly there is opportunity to work at the point of care, helping with patient investigation. 98-03-3, Name is Thiophene-2-aldehyde, molecular formurla is C5H4OS. In a document, author is Mantelingu, Kempegowda, introducing its new discovery. Electric Literature of 98-03-3.
Azomethine ylides are accessed under mild conditions via benzoic acid catalyzed condensations of 1,2,3,4-tetrahydroisoquinolines or tryptolines with aldehydes bearing a pendent dipolarophile. These intermediates undergo intramolecular [3 + 2]-cycloadditions in a highly diastereoselective fashion to form polycyclic amines with four new stereogenic centers. Challenging substrates such as piperidine, morpholine, and thiomorpholine undergo the corresponding reactions at elevated temperatures.
Electric Literature of 98-03-3, In the meantime we’ve collected together some recent articles in this area about 98-03-3. to whet your appetite. Happy reading!
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem