Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. In an article, author is Han, Bei, once mentioned the application of 585-32-0, Name is 2-Phenylpropan-2-amine, molecular formula is C9H13N, molecular weight is 135.2062, MDL number is MFCD00134680, category is thiomorpholine. Now introduce a scientific discovery about this category, Synthetic Route of 585-32-0.
Thirteen thiomorpholine-bearing compounds were designed and synthesized as dipeptidyl peptidase IV (DPP-IV) inhibitors, with natural and non-natural L-amino acids as the starting materials. Their structures were characterized by H-1 NMR, C-13 NMR and HR-MS. The target compounds were screened for the DPP-IV inhibition, and the preliminary SAR result was obtained. Particularly, compounds 4c, 4d and 4f with good DPP-IV inhibition in vitro were further evaluated through a mouse oral glucose tolerance test (OGTT). The preliminary result showed the potential value for further studies on those thiomorpholine-bearing compounds as DPP-IV inhibitors. (C) 2011 Hai Hong Huang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
Synthetic Route of 585-32-0, In the meantime we’ve collected together some recent articles in this area about 585-32-0. to whet your appetite. Happy reading!
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem