Chemical Properties and Facts of 827-95-2

The design and synthesis of related molecules that are more effective, more selective, and less toxic than aspirin are important objectives of biomedical research. You can also check out more blogs about 827-95-2. SDS of cas: 827-95-2.

Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. In an article, author is Kralova, Petra, once mentioned the application of 827-95-2, Name is Sodium 3-nitrobenzoate, molecular formula is C7H4NNaO4, molecular weight is 189.1, MDL number is MFCD00051097, category is thiomorpholine. Now introduce a scientific discovery about this category, SDS of cas: 827-95-2.

Herein, we report the stereoselective synthesis of trisubstituted benzoxazino[4,3-b]{1,2,5}thiadiazepinone 6,6-dioxides from polymer-supported Fmoc-Ser(tBu)-OH and Fmoc-Thr(tBu)-OH. After the solid-phase synthesis of N-alkylated-Nsulfonylated intermediates using various 2-nitrobenzenesulfonyl chlorides and bromoketones, the target compounds were obtained via trifluoroacetic acid (TFA)-mediated cleavage from the resin, followed by cyclization of the diazepinone scaffold. Except for the threonine-based intermediates, the inclusion of triethylsilane (TES) in the cleavage cocktail yielded a specific configuration of the newly formed C-3 chiral center. The final cyclization resulted in minor or no inversion of the C-12a stereocenter configuration.

The design and synthesis of related molecules that are more effective, more selective, and less toxic than aspirin are important objectives of biomedical research. You can also check out more blogs about 827-95-2. SDS of cas: 827-95-2.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem