While the job of a research scientist varies, most chemistry careers in research are based in laboratories, where research is conducted by teams following scientific methods and standards., Computed Properties of https://www.ambeed.com/products/35092-89-8.html, 35092-89-8, Name is 4-(Methoxycarbonyl)-3-nitrobenzoic acid, molecular formula is C9H7NO6, belongs to thiomorpholine compound. In a document, author is Ravula, Satheesh Babu, introduce the new discover.
The structure-activity relationships of 2-(piperidin-3-yl)-1H-benzimidazoles, 2-morpholine and 2-thiomorpholin-2-yl-1H-benzimidazoles are described. In the lead optimization process, the pK(a) and/or logP of benzimidazole analogs were reduced either by attachment of polar substituents to the piperidine nitrogen or incorporation of heteroatoms into the piperidine heterocycle. Compounds 9a and 9b in the morpholine series and 10g in the thiomorpholine series demonstrated improved selectivity and CNS profiles compared to lead compound 2 and these are potential candidates for evaluation as sedative hypnotics. (C) 2011 Elsevier Ltd. All rights reserved.
The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.you can check my other blog about 35092-89-8, you can contact me at any time and look forward to more communication. Computed Properties of https://www.ambeed.com/products/35092-89-8.html.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem