When developing chemical systems it’s of course important to gain a deep understanding of the chemical reaction process. In an article, author is He, Zhao-Lin, once mentioned the application of 100-21-0, Name is Terephthalic acid, molecular formula is C8H6O4, molecular weight is 166.1308, MDL number is MFCD00002558, category is thiomorpholine. Now introduce a scientific discovery about this category, Synthetic Route of 100-21-0.
A protocol of [3 + 3]-cycloaddition was proposed for the synthesis of 2H-1,4-thiazin-3(4H)-ones and thiomorpholine-3,5-diones from alpha-chlorohydroxamates and 1,4-dithiane-2,5-diol. This direct and practical method provides a novel and rapid approach for the synthesis of thiomorpholin-3-one derivatives under mild condition with moderate to good yield and wide functional group tolerance. (C) 2019 Elsevier Ltd. All rights reserved.
Synthetic Route of 100-21-0, You can get involved in discussing the latest developments in this exciting area about 100-21-0.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem