HPLC of Formula: C7H8N2O. Authors Ji, DZ; Zhang, WW; Xu, YG; Zhang, JJ in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Ji, Dezhong; Zhang, Wanwan; Xu, Yungen; Zhang, Jing-Jing] China Pharmaceut Univ, Dept Med Chem, Nanjing 210009, Peoples R China; [Xu, Yungen; Zhang, Jing-Jing] China Pharmaceut Univ, Jiangsu Key Lab Drug Design & Optimizat, Nanjing 210009, Peoples R China in 2020, Cited 15. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6
A series of anthranilamide derivatives were designed and synthesized as novel smoothened (SMO) inhibitors based on the SMO inhibitor taladegib (LY2940680), which can also inhibit the SMO-D473H mutant, via a ring-opening strategy. The phthalazine core in LY2940680 was replaced with anthranilamide, which retained the inhibitory activity towards the hedgehog (Hh) signaling pathway as evidenced by a dual luciferase reporter gene assay. Compound 12a displayed the best inhibitory activity against the Hh signaling pathway with IC50 value of 34.09 nM, and exhibited better proliferation inhibitory activity towards the Daoy cell line (IC50=0.48 mu M) than LY2940680 (IC50=0.79 mu M).
About 2-Aminobenzamide, If you have any questions, you can contact Ji, DZ; Zhang, WW; Xu, YG; Zhang, JJ or concate me.. HPLC of Formula: C7H8N2O
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem