Quality Control of 2-Aminobenzamide. I found the field of Chemistry very interesting. Saw the article A Green, Scalable, One-Minute Synthesis of Benzimidazoles published in 2020, Reprint Addresses Hansen, JH (corresponding author), UIT Arctic Univ Norway, Dept Chem, Chem Synth & Anal Div, Hansine Nansens Veg 54, N-9037 Tromso, Norway.. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide.
Herein is reported a substantially improved synthesis of 2-substituted benzimidazoles by condensation of 1,2-diaminoarenes and aldehydes using methanol as the reaction medium. The developed method afforded moderate to excellent yields (33-96%) at ambient temperature, displays high functional group tolerance, is conducted open to air, and requires only one minute reaction time under catalyst- and additive-free conditions. Moreover, the efficient protocol permits scale-up to multi-gram scale synthesis of benzimidazoles and will become a method of choice when constructing such heterocyclic systems.
About 2-Aminobenzamide, If you have any questions, you can contact Elumalai, V; Hansen, JH or concate me.. Quality Control of 2-Aminobenzamide
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem