Recently I am researching about CRYSTAL-STRUCTURE; MODULAR APPROACH; DERIVATIVES; CUCURBITURIL, Saw an article supported by the Tomsk State University. Computed Properties of C7H8N2O. Published in WILEY in HOBOKEN ,Authors: Bakibaev, AA; Uhov, A; Malkov, VS; Panshina, SY. The CAS is 64-10-8. Through research, I have a further understanding and discovery of 1-Phenylurea
Most of the known methods for the synthesis of heterocyclic compounds have disadvantages, such as a long reaction time and aggressive conditions. We have developed a new, rather simple and efficient method for the synthesis of a number of glycoluryls and hydantoins in water using a etidronic acid (HEDP) as Green catalyst. So, for the first time, the condensation reaction of ureas with 1, 2-dicarbonyl compounds was carried out in the presence of HEDP. Also based on NMR studies, a chemism of these reactions, which is stepwise, is proposed. It has been established that the optimal conditions for the synthesis of glycoluryls and hydantoins using HEDP are: temperature 80 degrees C-90 degrees C, 40-20 minutes, and the ratio of urea and HEDP is 1:1. In all cases, the remaining aqueous filtrate containing HEDP after the reaction can be reused for other cycles synthesis of glycoluril and other compounds, because HEDP is not converted during the reaction.
About 1-Phenylurea, If you have any questions, you can contact Bakibaev, AA; Uhov, A; Malkov, VS; Panshina, SY or concate me.. Computed Properties of C7H8N2O
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem