Day: October 25, 2021

Category: thiomorpholine. Recently I am researching about GREEN SYNTHESIS; BIOLOGICAL EVALUATION; ASSISTED SYNTHESIS; EFFICIENT; CATALYST; 2,3-DIHYDROQUINAZOLIN-4(1H)-ONES; QUINAZOLINONES; FACILE, Saw an article supported by the University of Guilan. Published in BENTHAM SCIENCE PUBL LTD in SHARJAH ,Authors: Sina, KF; Yahyazadeh, A; Mahmoodi, NO. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide

2, 3-Dihydroquinazolinones are of popular compounds with the diversification of biological and pharmacological activities. Among many discovered methods, there are efficient and convenient methods used for the synthesis of 2, 3-dihydroquinazoline-4 (1H)-one and some new bis 2, 3-dihydroquinazoline-4 (1H)-one derivatives which are reported in this study. The mentioned methods include the two-component condensation of one molecule of anthranilamide and one molecule of pyrazole carbaldehyde using montmorillonite-K 10 as a catalyst for the preparation of 2, 3 dihydroquinazoline-4 (1H)-ones. Also, one-pot pseudo-five-component reaction (5MCRs) of two molecules of isatoic anhydride, two molecules of pyrazole carbaldehydes and one molecule of ethan-1, 2-diamine in the presence of the r catalyst (montmorillonite-K10) for the synthesis of bis 2, 3-dihydroquinazoline-4 (1H)-ones. Despite the short times of reactions, high yields of products were obtained, which were validated using FT-IR, (HNMR)-H-1, (CNMR)-C-13, and elemental analysis. Moreover, the compounds were screened for their antimicrobial activities against two-gram-positive bacterial strains: Staphylococcus aureus and Micrococcus Luteus; and against two-gram-negative bacterial strains, as well: Escherichia coli and Pseudomonas aeruginosa, which all were utilized for antibacterial investigations. The results showed moderate or significant antibacterial activities.

About 2-Aminobenzamide, If you have any questions, you can contact Sina, KF; Yahyazadeh, A; Mahmoodi, NO or concate me.. Category: thiomorpholine

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Safety of 3-Nitrobenzaldehyde. Recently I am researching about IMIDAZOLIUM HYDROGEN SULFATE; POT 3-COMPONENT SYNTHESIS; KNOEVENAGEL-MICHAEL REACTION; IONIC LIQUID; MULTICOMPONENT REACTIONS; EFFICIENT CATALYST; ACETOACETATE DERIVATIVES; AMIDOALKYL NAPHTHOLS; PROMOTED SYNTHESIS; REUSABLE CATALYST, Saw an article supported by the Shahid Chamran University of Ahvaz. Published in TAYLOR & FRANCIS LTD in ABINGDON ,Authors: Savari, A; Heidarizadeh, F. The CAS is 99-61-6. Through research, I have a further understanding and discovery of 3-Nitrobenzaldehyde

In this work, a tetradentate acidic catalyst based on pentaerythritol tetrabromide and methylimidazole was designed and synthesized. The catalyst was characterized by Fourier transform infrared, H-1 NMR, C-13 NMR, and thermogravimetric analysis and its catalytic activity in the synthesis of 1-amidoalkyl-2-naphthols (from 2-naphthol, aryl aldehydes, and amide) and 4,4 ‘-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazole-5-ol)s (from aryl aldehydes, phenylhydrazine, and ethyl acetoacetate), two important classes of compounds, was investigated. The catalyst has multiple interesting properties such as hydrogen bonding interactions, high catalytic activity, heterogeneous feature, and ability to be useful under solvent-free condition.

About 3-Nitrobenzaldehyde, If you have any questions, you can contact Savari, A; Heidarizadeh, F or concate me.. Safety of 3-Nitrobenzaldehyde

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

I found the field of Chemistry very interesting. Saw the article Synthesis and Reactivity of 3 ‘,5 ‘-Dichloro-1H-spiro(quinazoline-2,4 ‘-[1,2,6]thiadiazin)-4(3H)-ones published in 2019. Name: 2-Aminobenzamide, Reprint Addresses Kalogirou, AS (corresponding author), European Univ Cyprus, Dept Life Sci, 6 Diogenis Str,POB 22006, CY-1516 Nicosia, Cyprus.; Kalogirou, AS (corresponding author), Univ Cyprus, Dept Chem, POB 20537, CY-1678 Nicosia, Cyprus.. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide

A three-step synthesis of 3 ‘,5 ‘-dichloro-1H-spiro(quinazo-line-2,4 ‘-[1,2,6]thiadiazin)-4(3H)-ones starting from 3,4,4,5-tetra-chloro-4H-1,2,6-thiadiazine is presented. The latter reacts with 2-aminobenzonitriles to give 2-[(3,5-dichloro-4H-1,2,6-thiadiazin-4-ylid-ene)amino]benzonitriles, which affords, after hydration, the respective benzamides. Upon heating at reflux in EtOH or HFIP, the benzamides intramolecularly cyclize onto the thiadiazine C4 position to give 3 ‘,5 ‘-dichloro-1H-spiro(quinazoline-2,4 ‘-[1,2,6]thiadiazin)-4(3H)-ones. Single crystal X-ray crystallography supports the structure of two analogues. The chloride displacement of these new spiroquinazolinones was demonstrated by Stille coupling, and by reaction with methoxide to afford both the mono and bis-methoxy derivatives.

About 2-Aminobenzamide, If you have any questions, you can contact Kalogirou, AS; Kourtellaris, A; Koutentis, PA or concate me.. Name: 2-Aminobenzamide

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Quality Control of Benzophenone. I found the field of Marine & Freshwater Biology; Toxicology very interesting. Saw the article Potentiation of lethal and sub-lethal effects of benzophenone and oxybenzone by UV light in zebrafish embryos published in 2021.0, Reprint Addresses Goss, G (corresponding author), Univ Alberta, Dept Biol Sci, 11455 Saskatchewan Dr, Edmonton, AB T6G 2E9, Canada.; Goss, G (corresponding author), Natl Inst Nanotechnol, 11421 Saskatchewan Dr, Edmonton, AB T6G 2M9, Canada.; Goss, G (corresponding author), Univ Alberta, Off Environm Nanosafety, Edmonton, AB, Canada.. The CAS is 119-61-9. Through research, I have a further understanding and discovery of Benzophenone.

Benzophenones are widely used as organic UV filters in many personal care products, especially sunscreen, to protect humans from UV radiation. The increasing use of benzophenone class UV filters has raised concerns about the potential effects on the aquatic environment. These organic UV filters are designed to absorb UV light. However, to date, studies have not considered the potential of UV light to potentiate the toxicity of benzophenones in aquatic organisms. In this study using zebrafish embryos, we assessed the median lethal concentration (LC50) and sub-lethal effects of benzophenone and oxybenzone either under natural levels of UV light or under laboratory light conditions. The LC50 value in zebrafish embryos under both light conditions of oxybenzone was lower when compared to benzophenone. Interestingly, UV light significantly decreased the LC50 values (increased toxicity) of both benzophenone and oxybenzone. The presence of UV light induced a significant increase in hydroxyl radical formation and this was reflected in both increased SOD activity and lipid peroxidation in oxybenzone treated groups. Exposure to either benzophenone or oxybenzone also delayed hatching between 60 and 96 hpf when comparing to the control group while UV exposure further delayed hatching only in oxybenzone-exposed embryos. The results demonstrate the importance of involving UV light in toxicity testing for UV filters and provide much-need information on the UV-induced toxicity of benzophenone and oxybenzone under ecologically realistic conditions.

Quality Control of Benzophenone. About Benzophenone, If you have any questions, you can contact Zhang, YY; Shah, PC; Wu, F; Liu, PP; You, J; Goss, G or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Name: Benzophenone. Authors Barretta, C; Oreski, G; Feldbacher, S; Resch-Fauster, K; Pantani, R in MDPI published article about in [Barretta, Chiara; Oreski, Gernot; Feldbacher, Sonja] Polymer Competence Ctr Leoben GmbH, Roseggerstr 12, A-8700 Leoben, Austria; [Resch-Fauster, Katharina] Univ Leoben, Inst Mat Sci & Testing Plast, Otto Glockl Str 8, A-8700 Leoben, Austria; [Pantani, Roberto] Univ Salerno, Dept Ind Engn, Via Giovanni Paolo II, I-84084 Fisciano, Italy in 2021.0, Cited 43.0. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

The main focus of this work is to investigate the degradation behavior of two newly developed encapsulants for photovoltaic applications (thermoplastic polyolefin (TPO) and polyolefin elastomer (POE)), compared to the most widely used Ethylene Vinyl Acetate (EVA) upon exposure to two different artificial ageing tests (with and without ultraviolet (UV) irradiation). Additive composition, optical and thermal properties and chemical structure (investigated by means of Thermal Desorption Gas Chromatography coupled to Mass Spectrometry, UV-Visible-Near Infrared spectroscopy, Differential Scanning Calorimetry, Thermogravimetric Analysis and Fourier Transform-Infrared spectroscopy, respectively) of the analyzed polymers were monitored throughout the exposure to artificial ageing tests. Relevant signs of photo-oxidation were detectable for TPO after the UV test, as well as a depletion of material’s stabilizers. Signs of degradation for EVA and POE were detected when the UV dose applied was equal to 200 kW h m(-2). A novel approach is presented to derive information of oxidation induction time/dose from thermogravimetric measurements that correlate well with results obtained by using oxidation indices.

About Benzophenone, If you have any questions, you can contact Barretta, C; Oreski, G; Feldbacher, S; Resch-Fauster, K; Pantani, R or concate me.. Name: Benzophenone

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Name: Anthrone. Recently I am researching about PHOTOREDOX CATALYSIS; DEHYDROGENATIVE ARYLATION; INTRAMOLECULAR ACYLATION; LIGHT; ACCESS; FLUORENONES; DERIVATIVES; PYRIDINES; XANTHONE; ARENES, Saw an article supported by the Research Project of the Natural Science Foundation of Heilongjiang Province of China [B2018012]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Jiang, HS; Mao, GJ; Wu, HF; An, Q; Zuo, MH; Guo, WH; Xu, CZ; Sun, ZZ; Chu, WY. The CAS is 90-44-8. Through research, I have a further understanding and discovery of Anthrone

An efficient intramolecular radical cyclization reaction via photoredox catalysis was developed for the synthesis of dibenzocycloketone derivatives using methylene blue as a photosensitizer. This strategy could be widely used to synthesize large heterocycles due to the unique reactivity of phosphoranyl radicals formed by a polar/SET crossover between an aromatic carboxylic acid and a phosphine radical cation. Attractive features of this process include generation of an acyl radical by an inexpensive and metal-free photocatalyst, which effectively undergoes a cyclization process.

Name: Anthrone. About Anthrone, If you have any questions, you can contact Jiang, HS; Mao, GJ; Wu, HF; An, Q; Zuo, MH; Guo, WH; Xu, CZ; Sun, ZZ; Chu, WY or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Authors Khazanov, TM; Botcha, NK; Yergeshbayeva, S; Shatruk, M; Mukherjee, A in ELSEVIER SCIENCE SA published article about ZETA VALENCE QUALITY; GAUSSIAN-BASIS SETS; COPPER(II) COMPLEXES; CATALYTIC MECHANISM; BETA-MONOOXYGENASE; OLEFIN EPOXIDATION; COMPOUND I; ATOMS LI; OXO; MONONUCLEAR in [Khazanov, Thomas M.; Botcha, Niharika Krishna; Mukherjee, Anusree] Univ Alabama, Dept Chem, 301 Sparkman Dr, Huntsville, AL 35899 USA; [Yergeshbayeva, Sandugash; Shatruk, Michael] Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA in 2021, Cited 88. Name: Anthrone. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8

This work presents a detailed study of the reactivity of three mononuclear Cu-II complexes supported by derivatives of the tetradentate ligand N,N’-bis(2-pyridylmethyl)-1,2-ethylenediamine (bispicen). The Cu-II complexes are capable of performing C – H bond activation in the presence of NEt3 and H2O2 through what has been proposed computationally to be a [CuO](+) intermediate. A wavefunction-based quantum chemical investigation into the electronic structure of the proposed [CuO](+) intermediate reveals a triplet ground state predominantly consistent with an S = 1/2 Cu-II center ferromagnetically coupled to an oxyl radical, though contributions from the corresponding biradicaloid CM-oxen resonance structure may be nontrivial. Furthermore, correlation of the electronic structure of the proposed intermediate with analogous high-valent metal-oxo species capable of olefin epoxidation suggests that the Cu-II complexes might be also capable of olefin epoxidation in the presence of NEt3 and H2O2. To test this hypothesis experimentally, the Cu-II complexes are treated with NEt 3 and H2O2 in the presence of alkene substrates, resulting in the formation of epoxides.

Name: Anthrone. About Anthrone, If you have any questions, you can contact Khazanov, TM; Botcha, NK; Yergeshbayeva, S; Shatruk, M; Mukherjee, A or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Category: thiomorpholine. Authors Dipake, SS; Lande, MK; Rajbhoj, AS; Gaikwad, ST in SPRINGER published article about in [Dipake, Sudarshan S.; Lande, Machhindra K.; Rajbhoj, Anjali S.; Gaikwad, Suresh T.] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem, Aurangabad 431004, Maharashtra, India in 2021.0, Cited 44.0. The Name is 3-Nitrobenzaldehyde. Through research, I have a further understanding and discovery of 99-61-6

Zeolite ZSM-11 catalyst was prepared by hydrothermal method and characterized by FTIR, XRD, SEM, HRTEM, EDS, and BET analysis techniques. The catalyst shows good catalytic activity toward synthesis of 2,4,5-triarylimidazole derivatives which is prepared by using benzil, aldehyde and ammonium acetate in solvent-free condition. The reaction, one pot synthesis is highly adaptable and eco-friendly and has several merits such as short reaction time, mild reaction conditions, and high yield. The ease of reusability and recovery of catalyst for five consecutive reactions makes this protocol highly suitable. [GRAPHICS] .

About 3-Nitrobenzaldehyde, If you have any questions, you can contact Dipake, SS; Lande, MK; Rajbhoj, AS; Gaikwad, ST or concate me.. Category: thiomorpholine

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

I found the field of Plant Sciences; Pharmacology & Pharmacy; Integrative & Complementary Medicine very interesting. Saw the article Downregulation of inflammatory mediators by ethanolic extract of Bergenia ligulata (Wall.) in oxalate injured renal epithelial cells published in 2021.0. Safety of Benzophenone, Reprint Addresses Tandon, C (corresponding author), Amity Inst Biotechnol, Amity Univ Campus,Sect 125, Noida 201313, UP, India.. The CAS is 119-61-9. Through research, I have a further understanding and discovery of Benzophenone

Ethnopharmacological relevance: In the Indian traditional system of medicine, Bergenia ligulata (Wall.) Engl. has been used for treatment of umlithiasis. Its efficacious nature has led to its incorporation in various commercial herbal formulations such as Cystone and Neeri which are prescribed for kidney related ailments. Aim of the study: To assess whether ethanolic extract of B. ligulata can mitigate the cascade of inflammatory responses that cause oxidative stress and ultimately cell death in renal epithelial cells exposed to hyperoxaluric conditions. Material and methods: Bioactivity guided fractionation using solvents of varying polarities was employed to evaluate the potential of the extracts of B. ligulata to inhibit the crystallization process. Modulation of crystal morphology was visualized through Scanning electron microscopy (SEM) analysis. Cell death was assessed using flow cytometry based assays. Alteration in the inflammatory mediators was evaluated using real time PCR and immunocytochemistry. Phytochemical characterization of the ethanolic extract was carried out using FTIR, LCMS and GC-MS. Results: Bioactivity guided fractionation for the assessment of antilithiatic activity revealed dose dependent inhibition of nucleation and aggregation process of calcium oxalate crystals in the presence of various extracts, however ethanolic extract showed maximum inhibition and was chosen for further experiments. Studies on renal epithelial NRK-52E cells showed, cytoprotective efficacy of B. ligulata extract against oxalate injury. SEM anaysis further revealed the potential of the extract to modulate the crystal structure and adhesion to renal cell surface. Exposure of the renal cells to the extract led to conversion of the calcium oxalate monohydrate (COM) crystals to the less injurious calcium oxalate dihydrate (COD) form. Expression analysis for oxidative stress and inflammatory biomarkers in NRK-52E cells revealed up-regulation of Mitogen activated protein kinase (MAPK), Osteopontin (OPN) and Nuclear factor-kappa B (NF-kappa B), in response to calcium oxalate insult; which was drastically reduced in the presence of B. ligulata extract. Flow cytometric evaluation pointed to caspase 3 mediated apoptotic cell death in oxalate injured cells, which was attenuated by B. ligulata extract. Conclusion: Considering the complex multifactorial etiology of urolithiasis, ethanolic extract from B. ligulata can be a promising option for the management of kidney stones, as it has the potential to limit inflammation and the subsequent cell death.

Safety of Benzophenone. About Benzophenone, If you have any questions, you can contact Singh, A; Tandon, S; Nandi, SP; Kaur, T; Tandon, C or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

COA of Formula: C14H10O. In 2019 BIOTECHNOL BIOFUELS published article about RICINUS-COMMUNIS L; FATTY-ACID; TRIACYLGLYCEROL BIOSYNTHESIS; CYPERUS-ESCULENTUS; ARABIDOPSIS; THIOESTERASE; RICINOLEATE; SYNTHETASE; METABOLISM; INCREASES in [Wan, Xia; Huang, Feng-Hong] Chinese Acad Agr Sci, Oil Crops Res Inst, Wuhan 430062, Hubei, Peoples R China; [Wan, Xia; Liu, Qing; Dong, Bei; Pillai, Sapna Vibhakaran; Singh, Surinder P.; Zhou, Xue-Rong] CSIRO Agr & Food, POB 1700, Canberra, ACT 2601, Australia; [Wan, Xia; Huang, Feng-Hong] Minist Agr, Key Lab Biol & Genet Improvement Oil Crops, Wuhan 430062, Hubei, Peoples R China; [Wan, Xia; Huang, Feng-Hong] Minist Agr, Key Lab Oilseeds Proc, Wuhan 430062, Hubei, Peoples R China; [Wan, Xia; Huang, Feng-Hong] Hubei Key Lab Lipid Chem & Nutr, Wuhan 430062, Hubei, Peoples R China in 2019, Cited 43. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8.

BackgroundWith the increasing demand for vegetative oil and the approach of peak seed oil production, it is important to develop new oil production platforms from non-seed tissues. Castor bean (Ricinus communis) is one of the crops for vegetable oil for industrial applications with yield around 1.4 ton oil per hectare produced in seed. The castor caruncle is a non-seed tissue attached to seed.ResultsCaruncle accumulates up to 40% oil by weight in the form of triacylglycerol (TAG), with a highly contrasting fatty acid composition when compared to the seed oil. Biochemical analysis indicated that the caruncle synthesizes TAGs independent of the seed. Such non-seed tissue has provided an excellent resource for understanding the mechanism of oil accumulation in tissues other than seeds. Transcriptome analysis revealed the key members of gene families involved in fatty acid synthesis and TAG assembly in the caruncle. A transient expression assay of these selected genes resulted in a 20-fold increased TAG accumulation in leaves.ConclusionsCastor caruncle utilizes an independent system to synthesize TAGs. Results provide the possibility of exploiting caruncle gene set to engineer oil production in non-seed tissues or microbes.

COA of Formula: C14H10O. About Anthrone, If you have any questions, you can contact Wan, X; Liu, Q; Dong, B; Pillai, SV; Huang, FH; Singh, SP; Zhou, XR or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem