I found the field of Chemistry very interesting. Saw the article Synthesis and Reactivity of 3 ‘,5 ‘-Dichloro-1H-spiro(quinazoline-2,4 ‘-[1,2,6]thiadiazin)-4(3H)-ones published in 2019. Name: 2-Aminobenzamide, Reprint Addresses Kalogirou, AS (corresponding author), European Univ Cyprus, Dept Life Sci, 6 Diogenis Str,POB 22006, CY-1516 Nicosia, Cyprus.; Kalogirou, AS (corresponding author), Univ Cyprus, Dept Chem, POB 20537, CY-1678 Nicosia, Cyprus.. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide
A three-step synthesis of 3 ‘,5 ‘-dichloro-1H-spiro(quinazo-line-2,4 ‘-[1,2,6]thiadiazin)-4(3H)-ones starting from 3,4,4,5-tetra-chloro-4H-1,2,6-thiadiazine is presented. The latter reacts with 2-aminobenzonitriles to give 2-[(3,5-dichloro-4H-1,2,6-thiadiazin-4-ylid-ene)amino]benzonitriles, which affords, after hydration, the respective benzamides. Upon heating at reflux in EtOH or HFIP, the benzamides intramolecularly cyclize onto the thiadiazine C4 position to give 3 ‘,5 ‘-dichloro-1H-spiro(quinazoline-2,4 ‘-[1,2,6]thiadiazin)-4(3H)-ones. Single crystal X-ray crystallography supports the structure of two analogues. The chloride displacement of these new spiroquinazolinones was demonstrated by Stille coupling, and by reaction with methoxide to afford both the mono and bis-methoxy derivatives.
About 2-Aminobenzamide, If you have any questions, you can contact Kalogirou, AS; Kourtellaris, A; Koutentis, PA or concate me.. Name: 2-Aminobenzamide
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem