Bhat, MA; Naglah, AM; Ansari, SA; Al-Tuwajiria, HM; Al-Dhfyan, A in [Bhat, Mashooq A.; Ansari, Siddique Akber; Al-Tuwajiria, Hanaa M.] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia; [Naglah, Ahmed M.] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Drug Explorat & Dev Chair DEDC, Riyadh 11451, Saudi Arabia; [Naglah, Ahmed M.] Natl Res Ctr, Peptide Chem Dept, Chem Ind Res Div, Cairo 12622, Egypt; [Al-Dhfyan, Abdullah] King Saud Univ, Coll Pharm, Dept Pharmacol & Toxicol, Riyadh 11451, Saudi Arabia; [Al-Dhfyan, Abdullah] King Faisal Specialized Hosp, Res Ctr, Stem Cell & Tissue Reengn Program, MBC 03,POB 3354, Riyadh 11211, Saudi Arabia published ChCl: Gly (DESs) Promote Environmentally Benign Synthesis of Xanthene Derivatives and Their Antitubercular Activity in 2021.0, Cited 59.0. Product Details of 99-61-6. The Name is 3-Nitrobenzaldehyde. Through research, I have a further understanding and discovery of 99-61-6.
A ChCl: Gly (DESs) promoted environmentally benign method was developed for the first time using the reaction of aryl aldehydes and dimedone to give excellent yields of xanthene analogues. The major application of this present protocol is the use of green solvent, a wide range of substrate, short reaction times, ease of recovery, the recyclability of the catalyst, high reaction yield, and ChCl: Gly as an alternative catalyst and solvent. In addition to this, all the synthesized compounds were evaluated for their in vitro antimycobacterial activity against M. tuberculosis H37Ra (MTB) and M. bovis BCG strains. The compounds 3d, 3e, 3f, and 3j showed significant antitubercular activity against MTB and M. bovis strains with minimum inhibitory concentration (MIC) values of 2.5-15.10 mu g/mL and 0.26-14.92 mu g/mL, respectively. The compounds 3e, 3f, and 3j were found to be nontoxic against MCF-7, A549, HCT 116, and THP-1 cell lines. All the prepared compounds were confirmed by H-1 NMR and C-13 NMR analysis.
About 3-Nitrobenzaldehyde, If you have any questions, you can contact Bhat, MA; Naglah, AM; Ansari, SA; Al-Tuwajiria, HM; Al-Dhfyan, A or concate me.. Product Details of 99-61-6
Reference:
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