Day: November 1, 2021

An article T3P mediated intramolecular rearrangement of o-aminobenzamide to o-ureidobenzonitrile using isothiocyanates WOS:000616581600001 published article about PRIMARY AMIDES; UREA; DISCOVERY; DERIVATIVES; INHIBITORS; AMINES; TRANSFORMATION; EFFICIENT; KINASE; MAP in [Shamanth, Sadashivamurthy; Sagar, Kunigal S.; Narayana, Yatheesh; Rangappa, Kanchugarakoppal S.; Kempegowda, Mantelingu] Univ Mysore, DOS Chem, Manasagangotri, Mysuru 570006, Karnataka, India; [Nagarakere, Sandhya C.] St Philomenas Coll, PG Dept Studies Chem, Mysuru, India; [Nagarakere, Sandhya C.] St Philomenas Coll, Res Ctr, Mysuru, India; [Mamatha, Mahesha] SRSMN Govt First Grade Coll, Barkur, India in 2021, Cited 38. Quality Control of 2-Aminobenzamide. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6

Current work describes the environmentally benign approach for the synthesis of o-ureidobenzonitriles, from o-aminobenzamides and isothiocyanates using T3P. Here, the conversion of thiourea to urea and amide to nitrile take place simultaneously via unprecedented intramolecular rearrangement. This protocol is operationally facile and offers wide variety of o-ureidobenzonitriles at room temperature in good to excellent yields.

Quality Control of 2-Aminobenzamide. About 2-Aminobenzamide, If you have any questions, you can contact Shamanth, S; Nagarakere, SC; Sagar, KS; Narayana, Y; Mamatha, M; Rangappa, KS; Kempegowda, M or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Authors Ike, PTL; Birolli, WG; dos Santos, DM; Porto, ALM; Souza, DHF in SPRINGER HEIDELBERG published article about POLYCYCLIC AROMATIC-HYDROCARBONS; TRAMETES-VERSICOLOR; OXIDATION; DEGRADATION; PURIFICATION; ENZYMES in [Leme Ike, Priscila Tomie; Ferreira Souza, Dulce Helena] Univ Fed Sao Carlos, Ctr Ciencias Exatas & Tecnol, Dept Quim, Rodovia Washington Luis,Km 235, BR-13565905 Sao Carlos, SP, Brazil; [Leme Ike, Priscila Tomie] Inst Fed Parana, Rua Antonio Carlos Rodrigues 453, BR-87703539 Paranagua, PR, Brazil; [Birolli, Willian Garcia; dos Santos, Danilo Martins; Meleiro Porto, Andre Luiz] Univ Sao Paulo, Lab Quim Organ & Biocatalise, Inst Quim Sao Carlos, Av Joao Dagnone 1100,Ed Quim Ambiental, BR-13563120 Sao Carlos, SP, Brazil in 2019, Cited 42. Recommanded Product: Anthrone. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8

Laccases produced by Leucoagaricus gongylophorus act in lignocellulose degradation and detoxification processes. Therefore, the use of L. gongylophorus laccase (Lac1Lg) was proposed in this work for degradation of anthracene and others polycyclic aromatic hydrocarbons without the use of mediators. Degradation reactions were performed in buffer aqueous solution with 10 ppm of anthracene and other PAHs, Tween-20 in 0.25% v/v and a laccase preparation of 50 U. The optimum condition (pH 6.0 and 30 degrees C) was determined by response surface methodology with an excellent coefficient of determination (R-2) of 0.97 and an adjusted coefficient of determination (R-adj(2)) of 0.93. In addition, the employment of the mediator ABTS decreased the anthracene biodegradation from 44 +/- 1% to 30 +/- 1%. This optimum pH of 6.0 suggests that the reaction occurs by a hydrogen atom transfer mechanism. Additionally, in 24 h Lac1Lg biodegraded 72 +/- 1% anthracene, 40 +/- 3% fluorene and 25 +/- 3% phenanthrene. The yellow laccase from L. gongylophorus biodegraded anthracene and produced anthrone and anthraquinone, which are interesting compounds for industrial applications. Moreover, this enzyme also biodegraded the PAHs phenanthrene and fluorene justifying the study of Lac1Lg for bioremediation of these compounds in the environment.

Recommanded Product: Anthrone. About Anthrone, If you have any questions, you can contact Ike, PTL; Birolli, WG; dos Santos, DM; Porto, ALM; Souza, DHF or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Name: Anthrone. In 2019 SCI TOTAL ENVIRON published article about POLYCYCLIC AROMATIC-HYDROCARBONS; BACKGROUND CONCENTRATIONS; BIOACCESSIBILITY; EXPOSURE; SURFACE in [Gao, Peng; da Silva, Evandro B.; Xiang, Ping; Ma, Lena Q.] Southwest Forestry Univ, Inst Environm Remediat & Human Hlth, Kunming 650224, Yunnan, Peoples R China; [Gao, Peng; Xu, Min; da Silva, Evandro B.; Ma, Lena Q.] Univ Florida, Soil & Water Sci Dept, Gainesville, FL 32611 USA; [Xu, Min] Sichuan Agr Univ, Coll Environm Sci, Chengdu 611130, Sichuan, Peoples R China; [Liu, Yalan] Univ Florida, Dept Environm Engn Sci, Gainesville, FL 32611 USA in 2019, Cited 20. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8.

Polycyclic aromatic hydrocarbons (PAHs) are widespread organic contaminants in the environment, much being accumulated in soils. Although their concentrations in large cities have been studied, their levels in small cities were less studied. This study determined the concentrations, distributions, and sources of 16 USEPA priority PAHs (legacy PAHs) and 6 emerging PAHs in urban soils of four small cities. A total of 100 soil samples were collected in Florida, USA. The average Sigma 16-PAHs in urban soils of Clay county, Ocala, Pensacola, and West Palm Beach were 1821, 2748, 3115 and 4055 mu g kg(-1), respectively. Based on benzo[a]pyrene-equivalent (BaP-EQ), the 7 USEPA carcinogenic PAHs (7cPAHs) and 3 emerging carcinogenic PAHs (3cPAHs) in urban soils in Clay County averaged 223 and 3703, Ocala 319 and 4521, Pensacola 302 and 5423, and West Palm Beach 449 and 5916 mu g kg(-1), respectively. Although Sigma 7cPAHs in 87-89% of samples were lower than the Florida Soil Cleanup Target Levels (FSCTLs) for industrial sites at 700 mu g kg(-1), Sigma 3cPAHs were 13-18 times greater than Sigma 7cPAHs. Based on the PMF model and molecular diagnostic ratios, soil PAHs were dominated by similar sources in small cities, mainly from pyrogenic sources including biomass, coal and coke combustion and vehicle emissions. It is important to evaluate both legacy and emerging PAHs concentrations in urban soils when considering soil remediation and human health risk assessment. (C) 2019 Published by Elsevier B.V.

About Anthrone, If you have any questions, you can contact Gao, P; Xu, M; Liu, YL; da Silva, EB; Xiang, P; Ma, LNQ or concate me.. Name: Anthrone

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

I found the field of Neurosciences & Neurology; Surgery very interesting. Saw the article Virtual education in neurosurgery during the COVID-19 pandemic published in 2020.0. Name: 1-Phenylurea, Reprint Addresses Patel, AJ (corresponding author), Baylor Coll Med, Houston, TX 77030 USA.. The CAS is 64-10-8. Through research, I have a further understanding and discovery of 1-Phenylurea

OBJECTIVE Neurosurgical education in the US has changed significantly as a consequence of the novel coronavirus (COVID-19) pandemic. Institutional social distancing requirements have resulted in many neurosurgical programs utilizing video conferencing for educational activities. However, it is unclear how or if these practices should continue after the pandemic. The objective of this study was to characterize virtual education in neurosurgery and understand how it should be utilized after COVID-19. METHODS A 24-question, 3-part online survey was administered anonymously to all 117 US neurosurgical residency programs from May 15, 2020, to June 15, 2020. Questions pertained to the current use of virtual conferencing, preferences over traditional conferences, and future inclinations. The Likert scale (1 = strongly disagree, 3 = neutral, 5 = strongly agree) was used. Comparisons were calculated using the Mann-Whitney U-test. Statistical significance was set at 0.05. RESULTS One-hundred eight responses were recorded. Overall, 38 respondents (35.2%) were attendings and 70 (64.8%) were trainees. Forty-one respondents (38.0%) indicated attending 5-6 conferences per week and 70 (64.8%) attend national virtual conferences. When considering different conference types, there was no overall preference (scores < 3) for virtual conferences over traditional conferences. In regard to future use, respondents strongly agreed that they would continue the practice at some capacity after the pandemic (median score 5). Overall, respondents agreed that virtual conferences would partially replace traditional conferences (median score 4), whereas they strongly disagreed with the complete replacement of traditional conferences (median score 1). The most common choices for the partial replacement of tradition conferences were case conferences (59/108, 55%) and board preparation (64/108, 59%). Lastly, there was a significant difference in scores for continued use of virtual conferencing in those who attend nationally sponsored conferences (median score 5, n = 70) and those who do not (median score 4, n = 38; U = 1762.50, z = 2.97, r = 0.29, p = 0.003). CONCLUSIONS Virtual conferences will likely remain an integral part of neurosurgical education after the COVID-19 pandemic has abated. Across the country, residents and faculty report a preference for continued use of virtual conferencing, especially virtual case conferences and board preparation. Some traditional conferences may even be replaced with virtual conferences, in particular those that are more didactic. Furthermore, nationally sponsored virtual conferences have a positive effect on the preferences for continued use of virtual conferences. https:// thejns.org/doi/abs/10.3171/2020.9.FOCUS20672 Name: 1-Phenylurea. About 1-Phenylurea, If you have any questions, you can contact Lazaro, T; Srinivasan, VM; Rahman, M; Asthagiri, A; Barkhoudarian, G; Chambless, LB; Kan, P; Rao, G; Nahed, BV; Patel, AJ or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Category: thiomorpholine. I found the field of Chemistry very interesting. Saw the article Synthesis, structure, characterization and biological evaluation of 3-substituted 1-pyridin-2-ylimidazo[1,5-a]pyridine-based copper(I)-phosphine complexes for anticancer drug screening published in 2021, Reprint Addresses Velusamy, M (corresponding author), North Eastern Hill Univ, Dept Chem, Shillong 793022, Meghalaya, India.; Murali, M (corresponding author), Natl Coll Autonomous, Dept Chem, Coordinat & Bioinorgan Chem Res Lab, Tiruchirappalli 620001, Tamil Nadu, India.. The CAS is 99-61-6. Through research, I have a further understanding and discovery of 3-Nitrobenzaldehyde.

Copper(I) complexes of the types [Cu(N-N)(PPh3)(2)]NO3(LC41-LC44) and [Cu(N-N)(PPh3)(NO3)] (LC45) carrying 3-substituted 1-pyridine-2-ylimidazo[1,5-a]pyridine (N-N) derivatives and triphenylphosphine (PPh3) ligands have been prepared. The synthesized copper(I)-phosphine complexes were fully characterized by NMR, IR, ESI-MS and UV-visible spectroscopy as well as by cyclic voltammetry. Selected structures such as LC42, LC43 and LC45 were additionally analysed by single-crystal X-ray method, which show that copper(I) centre adopts a highly distorted tetrahedral geometry. The(1)H and(13)C NMR spectral data of the complexes throw light on the nature of metal-ligand bonding. They display d pi-pi* metal-to-ligand charge transfer (MLCT) transition and show quasireversible Cu-I/Cu(II)metal oxidation. Among the copper(I)-phosphine complexes, LC41-LC44 exhibit moderate cytotoxicity (IC50: 24 h, 67-74 mu M; 48 h, 58-70 mu M) against human lung epithelial adenocarcinoma A549 cells, whereas LC45 displays the best activity (IC50: 24 h, 42 mu M; 48 h, 34 mu M) for A549 cancer cell line, which is better than that of the commercial antitumor drug cisplatin. All the complexes also displayed excellent selectivity by being relatively inactive against the human lung epithelial L132 normal cell line with selectivity index (SI) values ranging from 3.4 to 7.4. The complexes block cell cycle progression of A549 cells in G(0)/G(1)phase. FACSVerse analyses are suggestive of reactive oxygen species (ROS) generation and apoptotic cell death induced by the LC41, LC43 and LC45. The induction of apoptosis in A549 cells was shown by Annexin V with propidium iodide (PI) and 4 ‘,6-diamidino-2-phenylindole (DAPI) staining methods and established the ability of LC41, LC43 and LC45 to accumulate in the cell nuclei.

Category: thiomorpholine. About 3-Nitrobenzaldehyde, If you have any questions, you can contact Pathaw, L; Khamrang, T; Selvakumaran, B; Murali, M; Prakash, PA; Jaabir, MSM; Velusamy, M or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

In 2019 ACS APPL MATER INTER published article about VICKERS HARDNESS; PHOTOCYCLOADDITION; POLYURETHANE; DERIVATIVES; COMPOSITES; DEPENDENCE; ADDUCTS; SMART; GEL in [Hughes, Timothy; Saito, Kei] Monash Univ, Sch Chem, Clayton, Vic 3800, Australia; [Simon, George P.] Monash Univ, Dept Mat Sci & Engn, Clayton, Vic 3800, Australia in 2019, Cited 63. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8. Application In Synthesis of Anthrone

Two anthracene-based diamine crosslinkers were used to cure a range of commercially available monomers to produce four highly photoreversible crosslinked epoxy polymers. Through careful selection of the epoxy monomers used, the properties of the resultant polymer networks were varied to create a coating material that possessed room-temperature light-stimulated healing. Of the four coatings created, the best healing performance was exhibited by the two most flexible systems, both of these also exhibited the thermal and mechanical performance necessary for coatings. By using anthracene, the utilization of a wide range of wavelengths in the healing process is possible, which in applications such as industrial coatings would be of significant benefit.

Application In Synthesis of Anthrone. About Anthrone, If you have any questions, you can contact Hughes, T; Simon, GP; Saito, K or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Chromium- and Cobalt-Catalyzed, Regiocontrolled Hydrogenation of Polycyclic Aromatic Hydrocarbons: A Combined Experimental and Theoretical Study WOS:000470939200050 published article about ASYMMETRIC TRANSFER HYDROGENATION; CROSS-COUPLING REACTIONS; ENANTIOSELECTIVE HYDROGENATION; SELECTIVE HYDROGENATION; HOMOGENEOUS HYDROGENATION; GRIGNARD-REAGENTS; IRON; COMPLEXES; ARENES; ARYL in [Han, Bo; Zeng, Xiaoming] Xi An Jiao Tong Univ, Frontier Inst Sci & Technol, Xian 710054, Shaanxi, Peoples R China; [Zeng, Xiaoming] Sichuan Univ, Coll Chem, Chengdu 610064, Sichuan, Peoples R China; [Ma, Pengchen; Chen, Hui] Chinese Acad Sci, BNLMS, CAS Key Lab Photochem, CAS Res Educ Ctr Excellence Mol Sci,Inst Chem, Beijing 100190, Peoples R China; [Han, Bo] Yanan Univ, Coll Chem & Chem Engn, Shaanxi Key Lab Chem React Engn, Yanan 716000, Peoples R China; [Cong, Xuefeng] Northeast Normal Univ, Dept Chem, Changchun 130024, Jilin, Peoples R China in 2019, Cited 93. HPLC of Formula: C14H10O. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8

Polycyclic aromatic hydrocarbons are difficult substrates for hydrogenation because of the thermodynamic stability caused by aromaticity. We report here the first chromium- and cobalt-catalyzed, regiocontrolled hydrogenation of polycyclic aromatic hydrocarbons at ambient temperature. These reactions were promoted by low-cost chromium or cobalt salts combined with diimino/carbene ligand and methylmagnesium bromide and are characterized by high regioselectivity and expanded substrate scope that includes tetracene, tetraphene, pentacene, and perylene, which have rarely been reduced. The approach provides a cost-effective catalytic protocol for hydrogenation, is scalable, and can be utilized in the synthesis of tetrabromo- and carboxyl-substituted motifs through functionalization of the hydrogenation product. The systematic theoretical mechanistic modelings suggest that low-valent Cr and Co monohydride species, most likely from zerovalent transition metals, are capable of mediating these hydrogenations of fused PAHs.

About Anthrone, If you have any questions, you can contact Han, B; Ma, PC; Cong, XF; Chen, H; Zeng, XM or concate me.. HPLC of Formula: C14H10O

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Category: thiomorpholine. I found the field of Chemistry very interesting. Saw the article Synthesis and nematicidal evaluation of 1,2,3-benzotriazin-4-one derivatives containing piperazine as linker against Meloidogyne incognita published in 2019, Reprint Addresses Xu, XY (corresponding author), East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China.; Xu, XY (corresponding author), Shanghai Collaborat Innovat Ctr Biomfg Technol, Shanghai 200237, Peoples R China.. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide.

To explore new skeleton with nematicidal activity, a series of novel 1,2,3-benzotriazin-4-one derivatives containing piperazine as linker were synthesized and varied fragments were also introduced to increase structure diversity of the new skeleton. Their inhibitory activities in vivo were evaluated against Meloidogyne incognita. The newly prepared compounds A6, A8, A21, A28 and A38 exhibited more than 50% inhibition at the concentration of 20 mg/L. Especially compound A6 displayed 71.4% inhibition against Meloidogyne incognita at the concentration of 20 mg/L. The nematicidal activities varied significantly depending on the types and positions of the substituents, which provided guidance for further structure modification. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

Category: thiomorpholine. About 2-Aminobenzamide, If you have any questions, you can contact Chen, XL; Jia, HW; Li, Z; Xu, XY or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Application In Synthesis of Anthrone. Che, YM; Zhang, Z; Zhu, D; Hao, J; Hou, LX; Liu, X in [Che Yongmei; Zhang Zhen; Zhu Dan; Hao Jie; Hou Lixia; Liu Xin] Qingdao Agr Univ, Key Lab Plant Biotechnol Univ Shandong Prov, Coll Life Sci, Qingdao 266109, Shandong, Peoples R China published VvWRKY13 from Vitis vinifera negatively modulates salinity tolerance in 2019, Cited 38. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8.

WRKY transcription factors participate in the salt stress responses of various plant species, but the underlying functional mechanisms are not well understood, particularly in grape. In this study, the role of VvWRKY13 in the salt stress response was characterized and the underlying physiological and molecular mechanisms were explored. The results show that VvWRKY13 expression was induced by salt stress, and the VvWRKY13 transcript level in the salt stress-sensitive cultivar was significantly higher than that in the resistant cultivars. Overexpression of VvWRKY13 in Arabidopsis significantly inhibited the growth of transgenic plants under salt stress, indicating that VvWRKY13 has a negative effect on the salt stress response. The photosynthetic rate, contents of proline and soluble sugars, activities of superoxide dismutase (SOD) and catalase (CAT), as well as transcriptional levels of proline and soluble sugar metabolic genes, such as P5CS1, SS1, SS2 and G6PDH, as well as SOD and CAT encoding genes CAT1, CAT2, and Cu/Zn-SOD, all decreased under salt stress, whereas hydrogen peroxide and oxygen-free radical contents increased in transgenic Arabidopsis plants compared with those of wild-type plants. VvWRKY13 suppressed upregulation of SnRK2.3, ABF1, ABF2, ABF3, RD29B, RD29A, and RAB18 induced by salt stress, but showed no significant effect on the transcript levels of SnRK2.2, SnRK2.6, or RD22, indicating that VvWRKY13 affects salt stress tolerance via a specific abscisic acid signaling pathway. Key message VvWRKY13, isolated from grapevine, negatively regulate salt stress tolerance by depressing photosynthetic capacity, inhibiting salt-induced accumulation of osmolytes andup-regulation in antioxidant activity as well as expression of related genes. VvWRKY13 may affects salt stress tolerance by specific ABA signalling.

Application In Synthesis of Anthrone. About Anthrone, If you have any questions, you can contact Che, YM; Zhang, Z; Zhu, D; Hao, J; Hou, LX; Liu, X or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

I found the field of Chemistry very interesting. Saw the article Synthesis of Quinazoline and Quinazolinone Derivatives via Ligand-Promoted Ruthenium-Catalyzed Dehydrogenative and Deaminative Coupling Reaction of 2-Aminophenyl Ketones and 2-Aminobenzamides with Amines published in 2019. Category: thiomorpholine, Reprint Addresses Yi, CS (corresponding author), Marquette Univ, Dept Chem, Milwaukee, WI 53201 USA.. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide

The in situ formed ruthenium catalytic system ([Ru]/L) was found to be highly selective for the dehydrogenative coupling reaction of 2-aminophenyl ketones with amines to form quinazoline products. The deaminative coupling reaction of 2-aminobenzamides with amines led to the efficient formation of quinazolinone products. The catalytic coupling method provides an efficient synthesis of quinazoline and quinazolinone derivatives without using any reactive reagents or forming any toxic byproducts.

Category: thiomorpholine. About 2-Aminobenzamide, If you have any questions, you can contact Arachchige, PTK; Yi, CS or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem