Safety of 3-Nitrobenzaldehyde. Kaur, M; Kaushal, R in [Kaur, Mandeep; Kaushal, Raj] Natl Inst Technol, Dept Chem, Hamirpur 177005, Himachal Prades, India published Synthesis, characterization and alpha-amylase and alpha-glucosidase inhibition studies of novel vanadyl chalcone complexes in 2021, Cited 53. The Name is 3-Nitrobenzaldehyde. Through research, I have a further understanding and discovery of 99-61-6.
A series of chalcone ligands and their corresponding vanadyl complexes of composition [VO (LI-IV)(2)(H2O)(2)]SO4(where L-I= 1,3-Diphenylprop-2-en-1-one, L-II= 3-(2-Hydroxy-phenyl)-1-phenyl-propenone, L-III= 3-(3-Nitro-phenyl)-1-phenyl-propenone, L-IV= 3-(4-Methoxy-phenyl)-1-phenyl-propenone) have been synthesized and characterized using various spectroscopic (Fourier-transform infrared, electrospray ionization mass, nuclear magnetic resonance, electron paramagnetic resonance, thermogravimetric analysis, vibrating sample magnetometer) and physico-analytic techniques. Antidiabetic activities of synthesized complexes along with chalcones were evaluated by performing in vitro and in silico alpha-amylase and alpha-glucosidase inhibition studies. The obtained results displayed moderate to significant inhibition activity against both the enzymes by vanadyl chalcone complexes. The most potent complexes were further investigated for the enzyme kinetic studies and displayed the mixed inhibition for both the enzymes. Further, antioxidant activity of vanadyl chalcone complexes was evaluated for their efficiency to release oxidative stress using 2,2-diphenyl-1-picryl-hydrazyl-hydrate assay, and two complexes (Complexes2and4) have demonstrated remarkable antioxidant activity. All the complexes were found to possess promising antidiabetic and antioxidant potential.
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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem