An article PPTS-Catalyzed Bicyclization Reaction of 2-Isocyanobenzaldehydes with Various Amines: Synthesis of Diverse Fused Quinazolines WOS:000616361500001 published article about ONE-POT SYNTHESIS; NATURAL-PRODUCTS; MULTICOMPONENT REACTIONS; NITROGEN-HETEROCYCLES; CASCADE REACTIONS; ISOCYANIDE; CYCLIZATION; DERIVATIVES; ANNULATION; ACCESS in [Meng, Xiang-He; Wu, Dan-Ni; Zhang, Yu-Jia; Zhao, Yu-Long] Northeast Normal Univ, Jilin Prov Key Lab Organ Funct Mol Design & Synth, Fac Chem, Changchun 130024, Peoples R China in 2021, Cited 122. Recommanded Product: 2-Aminobenzamide. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6
A PPTS (pyridinium p-toluenesulfonate)-catalyzed bicyclization reaction of 2-isocyanobenzaldehydes as 1,5-dielectrophiles with various amines has been developed. The reaction not only provides a simple and efficient strategy for the assembly of structurally diverse fused quinazoline derivatives from readily available substrates under metal-free and mild conditions in a single step with only water and hydrogen as the by-products, but also opens the way to the application of o-formyl arylisocyanides in the synthesis of nitrogen-containing heterocycles.
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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem