Product Details of 99-61-6. I found the field of Chemistry very interesting. Saw the article Four-component, one-pot synthesis of (E)-N-benzylidene-3-(benzylthio)-5-(3,5-dimethyl-1H-pyrazol-1-yl)-4H-1,2,4-triazol-4-amines and their DNA binding and molecular docking studies published in 2021, Reprint Addresses Vedula, RR (corresponding author), Natl Inst Technol, Dept Chem, Warangal 506004, Telangana, India.. The CAS is 99-61-6. Through research, I have a further understanding and discovery of 3-Nitrobenzaldehyde.
An efficient four-component strategy has been developed for the synthesis of a novel series of (E)-N-benzylidene-3-(benzylthio)-5-(3,5-dimethyl-1H-pyrazol-1-yl)-4H-1,2,4-triazol-4-amines in good yields. The method is effective for the synthesis of benzylidene aralkyl/allyl/propargyl thio pyrazolyl-1,2,4-triazol-4-amines in a one-pot operation. This method is operationally simple, metal-free, and works under reflux conditions with diverse substrates. Among all the synthesized compounds 5a, b, c, h, j , and n were shown good results in silico studies. 5n is showing good results in both DNA binding and molecular docking studies. (C) 2020 Elsevier B.V. All rights reserved.
Product Details of 99-61-6. Welcome to talk about 99-61-6, If you have any questions, you can contact Jilloju, PC; Shyam, P; Sanjeev, A; Vedula, RR or send Email.
Reference:
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