An article 7-Endo-trig Pictet-Spengler type cyclization of 5-alkylidene/arylidene-amino-3H-pyrimidin-4-ones: An efficient and diastereoselective synthesis of pyrimido[4,5-b] [1,4]benzodiazepines WOS:000613773300001 published article about BIOLOGICAL EVALUATION; DERIVATIVES; DESIGN; AGENTS in [Naikoo, Rayees Ahmad; Kumar, Rupesh; Bhargava, Gaurav] IK Gujral Punjab Tech Univ Kapurthala, Dept Chem Sci, Kapurthala 144603, Punjab, India; [Singh, Parvesh] Univ KwaZulu Natal, Sch Chem & Phys, Durban, South Africa in 2021.0, Cited 49.0. Computed Properties of C7H5NO3. The Name is 3-Nitrobenzaldehyde. Through research, I have a further understanding and discovery of 99-61-6
The manuscript describes an efficient, atom economical synthesis of pyrimido[4,5-b][1,4]benzodiazepin-4-ones by relatively unexplored 7-endo-trig Pictet-Spengler type cyclisations. The synthetic methdodlogy involves the synthesis of different variants of 5-arylidene-amino-3H-pyrimidines and their p-toluene sulfonic acid mediated 7-endo-trig Pictet-Spengler type cyclisations to afford biologically relavent functionalized benzodiazepine condensed pyrimidinones such as pyrimido[4,5-b][1,4]benzodiazepines in good to excellent yields (82-94%).
Welcome to talk about 99-61-6, If you have any questions, you can contact Naikoo, RA; Kumar, R; Singh, P; Bhargava, G or send Email.. Computed Properties of C7H5NO3
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem