I found the field of Food Science & Technology very interesting. Saw the article Bioconversion by gut microbiota of predigested mango (Mangifera indica L) ‘Ataulfo’ peel polyphenols assessed in a dynamic (TIM-2) in vitro model of the human colon published in 2021.0. Safety of Benzophenone, Reprint Addresses Sayago-Ayerdi, SG (corresponding author), Tecnol Nacl Mexico, Inst Tecnol Tepic, Av Inst Tecnol 2595, Tepic 63175, Nayarit, Mexico.; Mateos, R (corresponding author), CSIC, Inst Food Sci Technol & Nutr ICTAN CSIC, Jose Antonio Novais 10, Madrid 28040, Spain.. The CAS is 119-61-9. Through research, I have a further understanding and discovery of Benzophenone
Gut microbiota bioconversion of polyphenols in predigested mango ‘Ataulfo’ peel was studied using a validated, dynamic in vitro human colon model (TIM-2) with faecal microbial inoculum. Dried peels were predigested with enzymatic treatment, followed by TIM-2 fermentation (72 h). Samples were taken at 0, 24, 48 and 72 h and analyzed by HPLC-QToF. Derivatives of hydroxyphenylpropionic, hydroxyphenylacetic and hydroxybenzoic acids, as well as, pyrogallol were the main polyphenols identified. These metabolites might derivate from flavonoid (flavanols and flavonols), gallate and gallotannin biotransformation. Despite the high content of ellagic acid in mango peel, low amounts were detected in TIM-2 samples due to transformation into urolythins A and C, mainly. Xanthone and benzophenone derivatives, specific to mango, remained after the colonic biotransformation, contrary to flavonoids, which completely disappeared. In conclusion, microbial-derived metabolites, such as xanthone and benzophenone derivatives, among others, are partially stable after colonic fermentation, and thus have the potential to contribute to mango peel bioactivity.
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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem