Quality Control of 2-Aminobenzamide. In 2020 NEW J CHEM published article about METAL-FREE SYNTHESIS; CYCLIZATION; ACCESS; CHEMORESISTANCE; QUINAZOLINONES; FLUORESCENCE; HETEROCYCLES; ALKALOIDS; CHEMISTRY; ALDEHYDES in [Bera, Anirban; Ali, Sk Asraf; Manna, Susanta Kumar; Samanta, Shubhankar] Bidhannagar Coll, Dept Chem, Kolkata 700064, India; [Bera, Anirban; Saha, Amit] Jadavpur Univ, Dept Chem, Kolkata 700032, India; [Ikbal, Mohammed] Berhampore Girls Coll, Dept Chem, Berhampur 742101, India; [Misra, Sandip] Bidhannagar Coll, Dept Microbiol, Kolkata 700064, India in 2020, Cited 54. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6.
An easy green synthetic approach for fused isoindoloquinazolinones has been developed under neat reaction (yields up to 91%) conditions. This new one-pot tandem methodology involves condensation of readily available anthranilamide with 3-(2-formylcycloalkenyl)-acrylic ester under solvent- and catalyst-free conditions. This strategy avoids the use of oxidant, and heavy metal catalysts and also is free from work-up and generation of toxic by-products. A dramatic change of photophysical properties of dihydroisoindoloquinazolinones in basic and aqueous media has also been documented in our study. Moreover, our model synthetic compound shows cytotoxic activity towards metastatic HepG2 and PC3 cancer cell lines.
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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem