Day: January 25, 2022

Authors Ghorbani, F; Pourmousavi, SA; Kiyani, H in BENTHAM SCIENCE PUBL LTD published article about IN-VITRO; BIOLOGICAL EVALUATION; EFFICIENT SYNTHESIS; REUSABLE CATALYST; ONE-POT; CELLULOSE; DESIGN; ADSORPTION; COMPOSITE; BEARING in [Ghorbani, Fatemeh; Pourmousavi, Seied Ali; Kiyani, Hamzeh] Damghan Univ, Sch Chem, Damghan 36715364, Iran; [Pourmousavi, Seied Ali] Damghan Univ, Inst Biol Sci, Damghan 3671641167, Iran in 2021, Cited 66. SDS of cas: 99-61-6. The Name is 3-Nitrobenzaldehyde. Through research, I have a further understanding and discovery of 99-61-6

In this report, SO3H-functionalized Carbon nanoparticles (Pine-SO3H) with high acid density have been synthesized by the thermal treatment of sulfuric acid with Pine-Cone as carbon-based at 180 degrees C in a sealed autoclave in a one-step procedure. The resulted Nanocatalyst was characterized by FT-IR, TGA, XRD, FE-SEM and elemental analysis (EA). The result of characterization was shown that the carbon-based acid is amorphous with polycyclic aromatic carbon sheets attached plentiful -OH, -COOH, and -SO3H groups. The catalytic activities of Pine-SO3H was investigated in the highly efficient synthesis of pyrano[2,3-c] pyrazole, amino-benzochromenes, amidoalkyl naphthol and 5-arylidene-2,4-thiazolidinedione derivatives. The application of Pine-SO3H in the synthesis offers several advantages such as simple procedure with an easy work-up, recoverable catalyst, mild condition, eco-friendliness, excellent yields, short reaction times and use of an inexpensive catalyst.

SDS of cas: 99-61-6. Welcome to talk about 99-61-6, If you have any questions, you can contact Ghorbani, F; Pourmousavi, SA; Kiyani, H or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Synthesis and characterization of some new Schiff base derivatives of gabapentin, and assessment of their antibacterial, antioxidant and anticonvulsant activities WOS:000614251000021 published article about OXIDATIVE STRESS; MODEL in [Saleem, Muhammad Farrukh; Khan, Mohsin Abbas; Ahmad, Irshad; Khurshid, Umair] Islamia Univ Bahawalpur, Fac Pharm & Alternat Med, Dept Pharmaceut Chem, Bahawalpur, Pakistan; [Aslam, Naveed] Govt Punjab, Primary & Secondary Healthcare Dept, Punjab, Pakistan in 2021.0, Cited 25.0. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9. Category: thiomorpholine

Purpose: To synthesize and characterize some new gabapentin Schiff base derivatives, and to assess their antibacterial, antioxidant and antiepileptic activities. Methods: Four Schiff base derivatives of gabapentin, termed G1, G2, G3 and G4, were synthesized by condensation with benzoin, vanillin, acetophenone, and benzophenone, respectively. Their chemical identities were established by FTIR, H-1 NMR and C-13 NMR techniques. The new compounds were screened for antibacterial activity using agar well method, antioxidant activity by DPPH assay, and anticonvulsant activity against pentylenetetrazole (PTZ) induced seizures in mice. Results: All the compounds showed antibacterial activity against the test strains to variable degrees, while the parent drug did not exhibit antibacterial activity. The zones of inhibition of compound G2 against Micrococcus luteus (36.2 +/- 1.0 mm) and Serratia marcescens (28.2 +/- 1.0 mm), and of compound G4 against Stenotrophomonas maltophilia (36.8 +/- 1.0 mm) were larger compared to the standard drug, doxycycline, exhibiting zones of inhibition 28.2 +/- 1.3, 28.2 +/- 0.9 and 20.0 +/- 0.9 mm, respectively. In addition, compounds G1 and G2 possessed significantly greater (p < 0.05) radical scavenging activity (82.3 +/- 1.8 and 92.3 +/- 2.2 %, respectively) than the precursor drug, gabapentin (63.2 +/- 2.6 %). The seizure scores for compounds GI (0.7 +/- 0.06) and G2 (0.9 +/- 0.07) were comparable (p > 0.05) with gabapentin (0.8 +/- 0.06), while compounds G3 and G4 were less active (p < 0.05) than gabapentin. Conclusion: Compounds G1 and G2 exhibit good antibacterial and antioxidant activities while retaining the anticonvulsant activity of the parent drug, gabapentin, thus making them suitable candidates for further development for the treatment of neurodegenerative pathologies associated with bacterial infections. Welcome to talk about 119-61-9, If you have any questions, you can contact Saleem, MF; Khan, MA; Ahmad, I; Aslam, N; Khurshid, U or send Email.. Category: thiomorpholine

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Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Product Details of 64-10-8. I found the field of Thermodynamics; Chemistry very interesting. Saw the article Experimental enthalpies of formation and sublimation of urea compounds: An accuracy assessment published in 2019.0, Reprint Addresses Dorofeeva, OV (corresponding author), Lomonosov Moscow State Univ, Fac Chem, 1-3 Leninskie Gory, Moscow 119991, Russia.. The CAS is 64-10-8. Through research, I have a further understanding and discovery of 1-Phenylurea.

The thermochemical network of 91 isodesmic and other balanced reactions was used to adjust simultaneously the enthalpies of formation of 14 urea compounds. The experimental enthalpies of formation of these compounds were treated as unknowns in the least-squares minimization of deviations between the theoretically predicted enthalpies of reaction and experimental values. A result of a least-squares fit confirms the accuracy of experimental enthalpies of formation of 8 ureas, whereas the experimental measurements for 6 urea compounds require re-examination. The gas-phase standard enthalpies of formation of 8 ureas were used as a consistent basis to obtain values for other 15 ureas through isodesmic reactions. To estimate the enthalpies of formation in crystalline state, the sublimation enthalpies were predicted using the molecular electrostatic potential model. (C) 2018 Elsevier Ltd.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recently I am researching about POT 3-COMPONENT SYNTHESIS; EFFICIENT SYNTHESIS; ACID; INHIBITORS; DERIVATIVES; SYSTEMS; AGENTS; NANOPARTICLES; CHEMISTRY, Saw an article supported by the Research Council of Yazd University. Published in TAYLOR & FRANCIS LTD in ABINGDON ,Authors: Safajoo, N; Mirjalili, BBF; Bamoniri, A. The CAS is 99-61-6. Through research, I have a further understanding and discovery of 3-Nitrobenzaldehyde. Product Details of 99-61-6

Fe3O4@NCs/Cu(II) as a bio-based magnetic nano-catalyst was prepared by adding CuCl2 to Fe3O4@NCs in alkaline medium. A series of indenopyrido [2,3-d] pyrimidines were synthesized by one-pot three-component reaction of 6-amino-2-(methylthio)pyrimidin-4(3H)-one, 1,3-indanedione and various aldehydes using Fe3O4@NCs/Cu(II) as an efficient and eco-friendly catalyst in ethanol at 60 degrees C. After completion of the reaction, the catalyst was separated by an external magnet and reused for the next experiment. Several advantages of this protocol are good yields, short reaction times, easy work-up and eco-friendly of the catalyst. The structure of the products were confirmed by elemental analyses, IR, H-1 NMR and C-13 NMR spectra. [GRAPHICS] .

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recently I am researching about 2,4-DICHLOROPHENOXYACETIC ACID; NUCLEOTIDE-SEQUENCE; INCP-1-BETA PLASMIDS; BACTERIAL CONSORTIUM; METABOLIC PATHWAY; DEGRADATION; RESISTANCE; TRANSPOSON; DIVERSITY; EVOLUTION, Saw an article supported by the Fonds voor Wetenschappelijk Onderzoek Vlaanderen (FWO)FWO [G.0371.06]; EU project METAEXPLORE (EU) [222625]; Deutsche ForschungsgemeinschaftGerman Research Foundation (DFG) [Sonderforschungsbereich TRR 51]; High Performance and Cloud Computing Group at the Zentrum fur Datenverarbeitung of the University of Tubingen; Federal Ministry of Education and Research (BMBF)Federal Ministry of Education & Research (BMBF) [031 A535A]; Leibniz Open Access Publishing Fund [4055]. Published in OXFORD UNIV PRESS in OXFORD ,Authors: Ozturk, B; Werner, J; Meier-Kolthoff, JP; Bunk, B; Sproer, C; Springael, D. The CAS is 64-10-8. Through research, I have a further understanding and discovery of 1-Phenylurea. Recommanded Product: 1-Phenylurea

Biodegradation of the phenylurea herbicide linuron appears a specialization within a specific Glade of the Variovorax genus. The linuron catabolic ability is likely acquired by horizontal gene transfer but the mechanisms involved are not known. The full-genome sequences of six linuron-degrading Variovorax strains isolated from geographically distant locations were analyzed to acquire insight into the mechanisms of genetic adaptation toward linuron metabolism. Whole-genome sequence analysis confirmed the phylogenetic position of the linuron degraders in a separate Glade within Variovorax and indicated that they unlikely originate from a common ancestral linuron degrader. The linuron degraders differentiated from Variovorax strains that do not degrade linuron by the presence of multiple plasmids of 20-839 kb, including plasmids of unknown plasmid groups. The linuron catabolic gene clusters showed 1) high conservation and synteny and 2) strain-dependent distribution among the different plasmids. Most of them were bordered by IS1071 elements forming composite transposon structures, often in a multimeric array configuration, appointing IS1071 as a key element in the recruitment of linuron catabolic genes in Variovorax. Most of the strains carried at least one (catabolic) broad host range plasmid that might have been a second instrument for catabolic gene acquisition. We conclude that Glade 1 Variovorax strains, despite their different geographical origin, made use of a limited genetic repertoire regarding both catabolic functions and vehicles to acquire linuron biodegradation.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

In 2019 ACS APPL MATER INTER published article about VICKERS HARDNESS; PHOTOCYCLOADDITION; POLYURETHANE; DERIVATIVES; COMPOSITES; DEPENDENCE; ADDUCTS; SMART; GEL in [Hughes, Timothy; Saito, Kei] Monash Univ, Sch Chem, Clayton, Vic 3800, Australia; [Simon, George P.] Monash Univ, Dept Mat Sci & Engn, Clayton, Vic 3800, Australia in 2019, Cited 63. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8. SDS of cas: 90-44-8

Two anthracene-based diamine crosslinkers were used to cure a range of commercially available monomers to produce four highly photoreversible crosslinked epoxy polymers. Through careful selection of the epoxy monomers used, the properties of the resultant polymer networks were varied to create a coating material that possessed room-temperature light-stimulated healing. Of the four coatings created, the best healing performance was exhibited by the two most flexible systems, both of these also exhibited the thermal and mechanical performance necessary for coatings. By using anthracene, the utilization of a wide range of wavelengths in the healing process is possible, which in applications such as industrial coatings would be of significant benefit.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

I found the field of Chemistry very interesting. Saw the article Electrochemical Synthesis of Carbodiimides via Metal/Oxidant-Free Oxidative Cross-Coupling of Amines and Isocyanides published in 2020. COA of Formula: C7H8N2O, Reprint Addresses Sharma, S (corresponding author), Mohanlal Sukhadia Univ, Dept Chem, Udaipur 313001, Rajasthan, India.. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide

This work discloses an electrochemical oxidative cross-coupling of amines with aryl and aliphatic isocyanides. In an undivided cell, the reaction proceeds without involving any transition-metal catalyst, oxidant, or toxic reagents providing carbodiimides in good yields, thereby circumventing stoichiometric chemical oxidants, with H-2 as the only byproduct. Moreover, carbodiimides were in situ converted into unsymmetrical ureas in moderate to good yields using an electricity ON-OFF strategy.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recently I am researching about DIENE METATHESIS POLYMERIZATION; QUATERNARY AMMONIUM POLYMERS; MICHAEL ADDITION; CHIRAL POLYMERS; ASYMMETRIC-SYNTHESIS; CATALYTIC-ACTIVITY; DESIGN; 1,5-HEXADIENE; NITROALKANES; DERIVATIVES, Saw an article supported by the . Published in MDPI in BASEL ,Authors: Ullah, MS; Chhanda, SA; Itsuno, S. The CAS is 90-44-8. Through research, I have a further understanding and discovery of Anthrone. Formula: C14H10O

Under the acyclic diene metathesis (ADMET) reaction condition, the C3-vinyl groups of cinchona alkaloids readily react with each other to form a C-C bond. A novel type of cinchona alkaloid polymers was synthesized from dimeric cinchona squaramides using the Hoveyda-Grubbs’ second-generation catalysts (HG(2)) by means of ADMET reaction. The chiral polymers, containing cinchona squaramide moieties in their main chains, were subsequently employed as catalysts for the enantioselective Michael reaction to give the corresponding chiral adducts in high yields with excellent enantioselectivity and diastereoselectivity. Both enantiomers from the asymmetric Michael reaction were distinctively prepared while using the polymeric catalysts, possessing pseudoenantiomeric structures. The catalysts were readily recovered from the reaction mixture and recycled several times due to the insolubility of the cinchona-based squaramide polymers.

Formula: C14H10O. Welcome to talk about 90-44-8, If you have any questions, you can contact Ullah, MS; Chhanda, SA; Itsuno, S or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Virtual education in neurosurgery during the COVID-19 pandemic WOS:000605455300007 published article about REALITY; SKILLS in [Lazaro, Tyler; Srinivasan, Visish M.; Rao, Ganesh; Patel, Akash J.] Baylor Coll Med, Dept Neurosurg, Houston, TX 77030 USA; [Patel, Akash J.] Baylor Coll Med, Dept Otolaryngol Head & Neck Surg, Houston, TX USA; [Rahman, Maryam] Univ Florida, Coll Med, Gainesville, FL USA; [Asthagiri, Ashok] Providence St Johns Hlth Ctr, John Wayne Canc Inst, Santa Monica, CA USA; [Barkhoudarian, Garni] Univ Virginia, Sch Med, Charlottesville, VA 22908 USA; [Chambless, Lola B.] Vanderbilt Univ, Dept Neurosurg, Sch Med, Nashville, TN USA; [Kan, Peter] Univ Texas Med Branch, Dept Neurosurg, Sch Med, Houston, TX USA; [Nahed, Brian, V] Harvard Med Sch, Dept Neurosurg, Boston, MA USA; [Patel, Akash J.] Texas Childrens Hosp, Jan & Duncan Neurol Res Inst, Houston, TX 77030 USA in 2020.0, Cited 10.0. SDS of cas: 64-10-8. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8

OBJECTIVE Neurosurgical education in the US has changed significantly as a consequence of the novel coronavirus (COVID-19) pandemic. Institutional social distancing requirements have resulted in many neurosurgical programs utilizing video conferencing for educational activities. However, it is unclear how or if these practices should continue after the pandemic. The objective of this study was to characterize virtual education in neurosurgery and understand how it should be utilized after COVID-19. METHODS A 24-question, 3-part online survey was administered anonymously to all 117 US neurosurgical residency programs from May 15, 2020, to June 15, 2020. Questions pertained to the current use of virtual conferencing, preferences over traditional conferences, and future inclinations. The Likert scale (1 = strongly disagree, 3 = neutral, 5 = strongly agree) was used. Comparisons were calculated using the Mann-Whitney U-test. Statistical significance was set at 0.05. RESULTS One-hundred eight responses were recorded. Overall, 38 respondents (35.2%) were attendings and 70 (64.8%) were trainees. Forty-one respondents (38.0%) indicated attending 5-6 conferences per week and 70 (64.8%) attend national virtual conferences. When considering different conference types, there was no overall preference (scores < 3) for virtual conferences over traditional conferences. In regard to future use, respondents strongly agreed that they would continue the practice at some capacity after the pandemic (median score 5). Overall, respondents agreed that virtual conferences would partially replace traditional conferences (median score 4), whereas they strongly disagreed with the complete replacement of traditional conferences (median score 1). The most common choices for the partial replacement of tradition conferences were case conferences (59/108, 55%) and board preparation (64/108, 59%). Lastly, there was a significant difference in scores for continued use of virtual conferencing in those who attend nationally sponsored conferences (median score 5, n = 70) and those who do not (median score 4, n = 38; U = 1762.50, z = 2.97, r = 0.29, p = 0.003). CONCLUSIONS Virtual conferences will likely remain an integral part of neurosurgical education after the COVID-19 pandemic has abated. Across the country, residents and faculty report a preference for continued use of virtual conferencing, especially virtual case conferences and board preparation. Some traditional conferences may even be replaced with virtual conferences, in particular those that are more didactic. Furthermore, nationally sponsored virtual conferences have a positive effect on the preferences for continued use of virtual conferences. https:// thejns.org/doi/abs/10.3171/2020.9.FOCUS20672 Bye, fridends, I hope you can learn more about C7H8N2O, If you have any questions, you can browse other blog as well. See you lster.. SDS of cas: 64-10-8

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Styryl quinazolinones and its ethynyl derivatives induce myeloid differentiation WOS:000480235700050 published article about C/EBP-ALPHA; INHIBITORS; CYTOTOXICITY; CANCER in [Radhakrishnan, Sridhar; Tenen, Daniel G.] Natl Univ Singapore, Canc Sci Inst Singapore, Singapore 117599, Singapore; [Syed, Riyaz; Sultana, Farheen; Kamal, Ahmed] Indian Inst Chem Technol, CSIR, Med Chem & Pharmacol, Hyderabad 500007, Andhra Pradesh, India; [Syed, Riyaz] Jawaharlal Nehru Technol Univ, Dept Chem, Hyderabad 500085, India; [Takei, Hisashi; Kobayashi, Ikei S.; Nakamura, Eugene; Kobayashi, Susumu S.] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA; [Takei, Hisashi; Kobayashi, Ikei S.; Nakamura, Eugene; Kobayashi, Susumu S.] Harvard Med Sch, Boston, MA 02215 USA; [Takei, Hisashi] Gunma Univ, Grad Sch Med, Dept Med & Clin Sci, Maebashi, Gunma 3718511, Japan; [Kamal, Ahmed] Janda Harndard, SPER, New Delhi 110062, India; [Tenen, Daniel G.] Harvard Med Sch, Harvard Stem Cell Inst, Boston, MA 02215 USA; [Kobayashi, Susumu S.] Natl Canc Ctr, Exploratory Oncol Res & Clin Trial Ctr, Div Translat Genom, Kashiwa, Chiba 2778577, Japan; [Sultana, Farheen] Wistar Inst Anat & Biol, 3601 Spruce St, Philadelphia, PA 19104 USA in 2019, Cited 21. Category: thiomorpholine. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6

The tumor suppressor transcription factor CCAAT enhancer-binding protein alpha (C/EBP alpha) expression is down-regulated in myeloid leukemias and enhancement of C/EBP alpha expression induces granulocytic differentiation in leukemic cells. Previously we reported that Styryl quinazolinones induce myeloid differentiation in HL-60 cells by upregulating C/EBP alpha expression. To identify more potent molecule that can induce leukemic cell differentiation we synthesized and evaluated new series of styryl quinazolinones, ethynyl styryl quinazolinones, styryl quinolinones and thienopyrimidinones. Thienopyrimidinones were found toxic and styryl quinolinones were found inactive. Ethynyl styryl quinazolinone 39 and styryl quinazolinone 5 were found active on par with the earlier reported analogues 1 and 2 suggesting that the 5-nitro furan-2-yl styryl quinazolinones find a real promise in leukemic cell differentiation. The improved potency of 5 suggested that further modifications in the 5-nitro furan-2-yl styryl quinazolinones can be at the phenyl substitution at the 3-position of the quinazolinone ring apart from the 5-position of the heteroaryl ring.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem