An article Palladium- catalysed regioselective N- arylation of anthranilamides: a tandem route for dibenzodiazepinone synthesis WOS:000468634300017 published article about OLANZAPINE; AMINATION; INDOLES; 1ST in [Laha, Joydev K.; Manral, Neelam; Hunjan, Mandeep Kaur] Natl Inst Pharmaceut Educ & Res, Dept Pharmaceut Technol Proc Chem, Sas Nagar 160062, Punjab, India in 2019, Cited 44. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6. Computed Properties of C7H8N2O
A palladium-catalyzed domino approach to the synthesis of 10,11-dihydro-5H-dibenzo[b,e][1,4]diazepinones from 2-aminobenzamides and 1,2-dihaloarenes has been developed. Our strategy integrating double N-arylations (inter- and intra-molecular) of 2-aminobenzamides with 1,2-dihaloarenes under palladium-catalyzed conditions is clearly distinct from the current literature available for the synthesis of dibenzodiazepinones. Unlike a previous report described for regioselective N-arylation of 2-aminobenzamide at the amine group, our mechanistic studies support the regioselective N-arylation of 2-aminobenzamide occurring first primarily at the amide group. The translational application of our protocol may be demonstrated in the synthesis of a marketed drug, clozapine.
Computed Properties of C7H8N2O. Welcome to talk about 88-68-6, If you have any questions, you can contact Laha, JK; Manral, N; Hunjan, MK or send Email.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem