Day: April 2, 2022

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Pheromone synthesis. Part 259: Synthesis of seven methyl-branched hydrocarbons as the pheromone candidates for female Korean apricot wasp, Eurytoma maslovskii, published in 2016-07-28, which mentions a compound: 616-14-8, mainly applied to pheromone synthesis Korean apricot wasp branched hydrocarbon, Synthetic Route of C5H11I.

Seven new methyl-branched hydrocarbons were synthesized, which were the pheromone candidates of the female Korean apricot wasp (Eurytoma maslovskii). They are (Z)-15-methyl-7-nonacosene (I), (Z)-17-methyl-7-hentriacontene (II), 3,7-dimethylheptacosane (III), 8,12-dimethyltriacontane (IV), 8,18-dimethyltriacontane (V), 3,7,11-trimethylnonacosane (VI), and 3,7,17-trimethylnonacosane (VII). All of them were synthesized as stereoisomeric mixtures, employing short and simple routes. Hydrocarbon VII was synthesized via 4,8-dimethyldecanal (tribolure), the red flour beetle pheromone. The hydrocarbons I, II, III and VI were identified by GC-MS anal. as the components (with unknown stereochem.) of the female-specific secretion of E. maslovskii.

There is still a lot of research devoted to this compound(SMILES：CCC(CI)C)Synthetic Route of C5H11I, and with the development of science, more effects of this compound(616-14-8) can be discovered.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Interaction of hydroxy compounds and phosphorus and thionyl halides in the absence and in the presence of tertiary bases. VI》. Authors are Berlak, Marianne C.; Gerrard, Wm..The article about the compound:1-Iodo-2-methylbutanecas:616-14-8,SMILESS:CCC(CI)C).Computed Properties of C5H11I. Through the article, more information about this compound (cas:616-14-8) is conveyed.

cf. C.A. 41, 93d. The following yields (in %) of alkyl iodide were obtained from the resp. alc. and 0.33 mol. PI3 in CS2 at 15-20° in 24 h. (other exptl. conditions indicated): PrOH 40; iso-PrOH 20 (72 h. 21; 1 mol. 18); BuOH 43 (72 h. 61, 2.5 h. at b.p. 48; 1 mol. for 24 or 72 h. 56); sec-BuOH 60 (72 h. 58; 1 mol. 61); tert-BuOH 20 (also 72 h.; 1 mol. 17); sec-BuCH2OH 48 (68 h. 44, 1 mol. 45); Pr2CHOH 74 (1 mol. 80); C8H17OH 42 (1 mol. 56); C6H13CH(Me)OH (I) 36 (0.66 mol. for 24 or 72 h. 66, 1 mol. 75). (+)-I (6.5 g.) and 3.95 g. C5H5N in 50 cc. CS2 at -10°, treated with 6.9 g. PI3, give 9.3 g. C5H5N.HI; further addition of 13.8 g. PI3 gives 7.78 g. C6H13CHIMe, αD18 -56.8% BuOH and C8H17OH show a similar behavior. (-)-Dimethylhexylcarbinyl H phosphite (4.6 g., αD22 -12.6°) at -10°, treated (1 h.) with HI and kept 18 h. at 15° gives 5.93 g. (+)-C6H13CHIMe, αD20 45.8°. (BuO)2PHO (6.5 g.), treated 50 min. at -10° with HI and kept 30 min. at -10°, gives 2.65 g. BuI; if the reaction is carried out without cooling (temperature rise from 19 to 23°), there results 5.3 g. BuI. (RO)2HPO react much more readily with HI than with HCl or HBr. The mechanism of the reaction is discussed.

There is still a lot of research devoted to this compound(SMILES：CCC(CI)C)Computed Properties of C5H11I, and with the development of science, more effects of this compound(616-14-8) can be discovered.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem

Recommanded Product: (R)-(9H-Fluoren-9-yl)methyl (1-chloro-4-methyl-1-oxopentan-2-yl)carbamate. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: (R)-(9H-Fluoren-9-yl)methyl (1-chloro-4-methyl-1-oxopentan-2-yl)carbamate, is researched, Molecular C21H22ClNO3, CAS is 198544-60-4, about Chemical genetics approach to identify new small molecule modulators of cell growth by phenotypic screening of Saccharomyces cerevisiae strains with a library of morpholine-derived compounds. Author is Trabocchi, Andrea; Stefanini, Irene; Morvillo, Manfredi; Ciofi, Leonardo; Cavalieri, Duccio; Guarna, Antonio.

A chem. genetics approach has been applied in the screening of yeast deletants strains with a pool of morpholine-derived compounds in order to identify candidate small mols. able to produce phenotypic effects on yeast cells. The anal. of the effects of structurally diverse mols. towards cell growth rate in both exponential and stationary phases provides a tool to select candidate compounds for subsequent assays to identify new chem. entities as chem. probes for drug discovery.

There is still a lot of research devoted to this compound(SMILES：O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@H](CC(C)C)C(Cl)=O)Recommanded Product: (R)-(9H-Fluoren-9-yl)methyl (1-chloro-4-methyl-1-oxopentan-2-yl)carbamate, and with the development of science, more effects of this compound(198544-60-4) can be discovered.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Vital signs: trends in use of long-acting reversible contraception among teens aged 15-19 years seeking contraceptive services—United States, 2005-2013.》. Authors are Romero, Lisa; Pazol, Karen; Warner, Lee; Gavin, Lorrie; Moskosky, Susan; Besera, Ghenet; Loyola Briceno, Ana Carolina; Jatlaoui, Tara; Barfield, Wanda; Centers for Disease Control and Prevention (CDC).The article about the compound:1-Iodo-2-methylbutanecas:616-14-8,SMILESS:CCC(CI)C).Recommanded Product: 616-14-8. Through the article, more information about this compound (cas:616-14-8) is conveyed.

BACKGROUND: Nationally, the use of long-acting reversible contraception (LARC), specifically intrauterine devices (IUDs) and implants, by teens remains low, despite their effectiveness, safety, and ease of use. METHODS: To examine patterns in use of LARC among females aged 15-19 years seeking contraceptive services, CDC and the U.S. Department of Health and Human Services’ Office of Population Affairs analyzed 2005-2013 data from the Title X National Family Planning Program. Title X serves approximately 1 million teens each year and provides family planning and related preventive health services for low-income persons. RESULTS: Use of LARC among teens seeking contraceptive services at Title X service sites increased from 0.4% in 2005 to 7.1% in 2013 (p-value for trend <0.001). Of the 616,148 female teens seeking contraceptive services in 2013, 17,349 (2.8%) used IUDs, and 26,347 (4.3%) used implants. Use of LARC was higher among teens aged 18-19 years (7.6%) versus 15-17 years (6.5%) (p<0.001). The percentage of teens aged 15-19 years who used LARC varied widely by state, from 0.7% (Mississippi) to 25.8% (Colorado). CONCLUSIONS: Although use of LARC by teens remains low nationwide, efforts to improve access to LARC among teens seeking contraception at Title X service sites have increased use of these methods. IMPLICATIONS FOR PUBLIC HEALTH PRACTICE: Health centers that provide quality contraceptive services can facilitate use of LARC among teens seeking contraception. Strategies to address provider barriers to offering LARC include: 1) educating providers that LARC is safe for teens; 2) training providers on LARC insertion and a client-centered counseling approach that includes discussing the most effective contraceptive methods first; and 3) providing contraception at reduced or no cost to the client. There is still a lot of research devoted to this compound(SMILES：CCC(CI)C)Recommanded Product: 616-14-8, and with the development of science, more effects of this compound(616-14-8) can be discovered.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Fumigation of agricultural products. XII. Sorption of methyl bromide on groundnuts》. Authors are Somade, H. M. B..The article about the compound:1-Iodo-2-methylbutanecas:616-14-8,SMILESS:CCC(CI)C).Safety of 1-Iodo-2-methylbutane. Through the article, more information about this compound (cas:616-14-8) is conveyed.

Sorption of MeBr on groundnuts (I) was studied with both undecorticated I and I separated into husk, cotyledon, and germ. Successful treatment of I with MeBr depended on the moisture content of the nuts. Impairment of germination following MeBr treatment was observed when the moisture content exceeded 5%. Sorption of MeBr was found to increase more rapidly than the dosage, necessitating careful dosage control. At concentrations lower than that critical for a particular moisture content and period of fumigation, a slight stimulating action of MeBr on germination was observed.

There is still a lot of research devoted to this compound(SMILES：CCC(CI)C)Safety of 1-Iodo-2-methylbutane, and with the development of science, more effects of this compound(616-14-8) can be discovered.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem

Application In Synthesis of 1-Iodo-2-methylbutane. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 1-Iodo-2-methylbutane, is researched, Molecular C5H11I, CAS is 616-14-8, about Gamma radiolysis of branched chain hydrocarbons. 2,3-Dimethylbutane. Author is Castello, Gianrico; Grandi, Francesco; Munari, Stelio.

The γ-radiolysis of liquid 2,3-dimethylbutane at room temperature was investigated under vacuum. Iodine was used as a free radical scavenger and the formed alkyl iodides were analyzed by gas chromatog. with electron capture detector. Irradiations of frozen 2,3-dimethylbutane at 77°K were also performed. The fragmentation products and many of those having a number of C atoms higher than the parent were identified and measured. The formation of the identified heavy products is mainly due to recombination of radicals, as demonstrated by the comparison between their yields and those of alkyl iodides.

There is still a lot of research devoted to this compound(SMILES：CCC(CI)C)Application In Synthesis of 1-Iodo-2-methylbutane, and with the development of science, more effects of this compound(616-14-8) can be discovered.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Imidazole series. XX. Aminonitroimidazoles and diaminoimidazoles》. Authors are Kochergin, P. M.; Verenikina, S. G.; Bushueva, K. S..The article about the compound:1-Methyl-4-nitro-1H-imidazol-5-aminecas:4531-54-8,SMILESS:NC1=C([N+]([O-])=O)N=CN1C).Computed Properties of C4H6N4O2. Through the article, more information about this compound (cas:4531-54-8) is conveyed.

cf. preceding abstract The aminonitroimidazoles I-XII were prepared by heating the corresponding nitrochloroimidazoles with a 8-15% alc. NH3 solution at 120-50° for 5-10 hrs. The products I, VII, and XII were obtained in the presence of CuSO4 catalyst (formula, R, m.p., and % yield 131-1.5°, 15-20; VII, iso-Bu, 108-10°, 15; VIII, H, 222.5-23°, 30.5; IX, Me, 198-9°, 39.5; X, Et, 160-1°, 58; XI, Pr, 130-1°, 32; XII, iso-Bu, 129-30°, 21.5. The hydrogenation of II in Ac2O in the presence of Raney Ni gave 1-ethyl-2-methyl-4,5-diaminoimidazole diacetate at 30-45° and initial H pressure of 10 atm. and tetraacetate at 50-80° and 100 atm.

There is still a lot of research devoted to this compound(SMILES：NC1=C([N+]([O-])=O)N=CN1C)Computed Properties of C4H6N4O2, and with the development of science, more effects of this compound(4531-54-8) can be discovered.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (R)-(9H-Fluoren-9-yl)methyl (1-chloro-4-methyl-1-oxopentan-2-yl)carbamate, is researched, Molecular C21H22ClNO3, CAS is 198544-60-4, about Total Solid Phase Syntheses of the Quinazoline Alkaloids: Verrucines A and B and Anacine.Electric Literature of C21H22ClNO3.

The first total syntheses of verrucines A and B and anacine (revised structure) were accomplished on Sasrin resin. This work confirmed the structure of verrucine A and unambiguously showed verrucine B to be a derivative of D-phenylalanine and L-glutamine. The study also proved that anacine and its epimer are quinazoline alkaloids, not benzodiazepines as originally proposed. 1-Hydroxyverrucine B, derived from air oxidization of verrucine B, was also isolated and characterized.

There is still a lot of research devoted to this compound(SMILES：O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@H](CC(C)C)C(Cl)=O)Electric Literature of C21H22ClNO3, and with the development of science, more effects of this compound(198544-60-4) can be discovered.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Cerebrospinal fluid lymphocytes in experimental allergic encephalomyelitis.》. Authors are Wilkerson, L D; Lisak, R P; Zweiman, B.The article about the compound:1-Iodo-2-methylbutanecas:616-14-8,SMILESS:CCC(CI)C).COA of Formula: C5H11I. Through the article, more information about this compound (cas:616-14-8) is conveyed.

We report characteristics of the cerebrospinal fluid (CSF) pleocytosis (616+/-148 cells/microliter) that occurred in guinea-pigs with definite clinical experimental allergic encephalomyelitis developing 12 to 16 days after sensitization with homologous myelin basic protein. This pleocytosis was not present in the cerebrospinal fluid of a group of animals studied when still healthy, 9 or 10 days after similar sensitization. Eighty-nine per cent of cells in the CSF pleocytosis were small lymphocytes, 8% were larger lymphocytes and the remainder mostly monocytes. Of the lymphocytes, most were E-rosetting or null cells. B-cell markers were uncommon. The cellular patterns in this CSF pleocytosis appear to be similar to those seen in some delayed hypersensitivity responses.

There is still a lot of research devoted to this compound(SMILES：CCC(CI)C)COA of Formula: C5H11I, and with the development of science, more effects of this compound(616-14-8) can be discovered.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem

Application In Synthesis of 1-Methyl-4-nitro-1H-imidazol-5-amine. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 1-Methyl-4-nitro-1H-imidazol-5-amine, is researched, Molecular C4H6N4O2, CAS is 4531-54-8, about A catalyst and additive-free three-component reaction of highly electrophilic azides with cyclic ketones and cycloaliphatic amines. Synthesis of novel N-heteroaryl amidines. Author is Efimov, Ilya; Beliaev, Nikolai; Beryozkina, Tetyana; Slepukhin, Pavel; Bakulev, Vasiliy.

Highly electrophilic 5-azido-1-methyl-4-nitro-1H-imidazole and sulfonyl azides were demonstrated to react with alicyclic amines and cyclic ketones in the absence of any catalyst or additive to afford novel N-(4-nitroimidazol-5-yl)- or N-sulfonylamidines resp. Based on single crystal X-ray anal., a revision of the previously reported data of Gao and co-workers on the direction of the reaction of sulfonyl azides with endocyclic enamines was made. The reaction of 2,6-diazidopyridine with an enamine, 4-(cyclohex-1-en-1-yl)morpholine, proceeded with cyclization of the azide moiety onto the pyridine C=N bond to form an amidine bearing the tetrazolo[1,5-a]pyridine fragment.

There is still a lot of research devoted to this compound(SMILES：NC1=C([N+]([O-])=O)N=CN1C)Application In Synthesis of 1-Methyl-4-nitro-1H-imidazol-5-amine, and with the development of science, more effects of this compound(4531-54-8) can be discovered.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem