So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Berthold, Dino; Breit, Bernhard researched the compound: 1-Iodo-2-methylbutane( cas:616-14-8 ).Computed Properties of C5H11I.They published the article 《Total Synthesis of (-)-Cylindrocyclophane F: A Yardstick for Probing New Catalytic C-C Bond-Forming Methodologies》 about this compound( cas:616-14-8 ) in Chemistry – A European Journal. Keywords: cylindrocyclophane F synthesis; C-allylation; Negishi coupling; cylindrocyclophane F; lactic acid; metathesis; total synthesis. We’ll tell you more about this compound (cas:616-14-8).
A short and efficient total synthesis of the C2-sym. (-)-cylindrocyclophane F is presented, using a cross olefin metathesis dimerization strategy for construction of the [7,7]-paracyclophane macrocycle. The synthesis of the dimerization building block includes a Pd-catalyzed sp3-sp2 Negishi cross coupling of a sterically hindered Zn-reagent with an aromatic triflate, an enantiospecific Zn-catalyzed sp3-sp3 cross coupling of an α-hydroxy ester triflate with a Grignard reagent and the application of an enantioselective Rh-catalyzed C-allylation of an electron rich arene.
There is still a lot of research devoted to this compound(SMILES：CCC(CI)C)Computed Properties of C5H11I, and with the development of science, more effects of this compound(616-14-8) can be discovered.
Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem