Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 4531-54-8, is researched, SMILESS is NC1=C([N+]([O-])=O)N=CN1C, Molecular C4H6N4O2Journal, Acta Poloniae Pharmaceutica called Nitroimidazoles. VI. Partition coefficients and tautomerism of simple nitroimidazoles, Author is Suwinski, Jerzy; Salwinska, Ewa; Watras, Jan; Widel, Maria, the main research direction is nitroimidazole derivative partition coefficient tautomerism.Reference of 1-Methyl-4-nitro-1H-imidazol-5-amine.
Octanol-water partition coefficients (P) were determined for 42 simple nitroimidazoles with Me, Cl, Br, MeO, NH2, and NO2 substituents. Correlation between log P and the substituent constants πX of Hansch and fX of Nys-Rekker was derived. For the N-methylated compounds, the average value of πN-CH3 was calculated to be -0.30. Significance of log P measurement in estimating the tautomeric equilibrium in 4(5)-nitroimidazoles is discussed in detail.
In addition to the literature in the link below, there is a lot of literature about this compound(1-Methyl-4-nitro-1H-imidazol-5-amine)Reference of 1-Methyl-4-nitro-1H-imidazol-5-amine, illustrating the importance and wide applicability of this compound(4531-54-8).
Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem