Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Chemical Science called Metal-free C(sp3)-H functionalization of sulfonamides via strain-release rearrangement, Author is Hu, Jiefeng; Yang, Xianyu; Shi, Shasha; Cheng, Bo; Luo, Xiaoling; Lan, Yu; Loh, Teck-Peng, which mentions a compound: 616-14-8, SMILESS is CCC(CI)C, Molecular C5H11I, COA of Formula: C5H11I.
A metal-free reaction system that enables C-H bond functionalization of aliphatic sulfonamides R(CH2)2N(F)Ts (R = decyl, cyclohexyl, oxan-4-yl, benzyl, etc.) using DABCO as a promoter under mild conditions, affording a series of α,β-unsaturated imines R1CH=C(R)CH=NTs (R1 = Ph, 4-chlorophenyl, 2,3-dihydro-1-benzofuran-5-yl, etc.) in good yields with high selectivities was presented. This protocol tolerates a broad range of functionalities and can serve as a powerful synthetic tool for the late-stage modification of complex compounds More importantly, control experiments and detailed DFT calculations suggest that this process involves [2 + 2] cyclization/ring-cleavage reorganization, which opens up a new platform for the establishment of other related reorganization reactions.
Compound(616-14-8)COA of Formula: C5H11I received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(1-Iodo-2-methylbutane), if you are interested, you can check out my other related articles.
Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem