So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Wang, Haishan; Sim, Mui Mui researched the compound: (R)-(9H-Fluoren-9-yl)methyl (1-chloro-4-methyl-1-oxopentan-2-yl)carbamate( cas:198544-60-4 ).Application In Synthesis of (R)-(9H-Fluoren-9-yl)methyl (1-chloro-4-methyl-1-oxopentan-2-yl)carbamate.They published the article 《Total Solid Phase Syntheses of the Quinazoline Alkaloids: Verrucines A and B and Anacine》 about this compound( cas:198544-60-4 ) in Journal of Natural Products. Keywords: verrucine A B total solid phase synthesis; anacine total solid phase synthesis structure; quinazoline alkaloid total solid phase synthesis. We’ll tell you more about this compound (cas:198544-60-4).
The first total syntheses of verrucines A and B and anacine (revised structure) were accomplished on Sasrin resin. This work confirmed the structure of verrucine A and unambiguously showed verrucine B to be a derivative of D-phenylalanine and L-glutamine. The study also proved that anacine and its epimer are quinazoline alkaloids, not benzodiazepines as originally proposed. 1-Hydroxyverrucine B, derived from air oxidization of verrucine B, was also isolated and characterized.
Although many compounds look similar to this compound(198544-60-4)Application In Synthesis of (R)-(9H-Fluoren-9-yl)methyl (1-chloro-4-methyl-1-oxopentan-2-yl)carbamate, numerous studies have shown that this compound(SMILES:O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@H](CC(C)C)C(Cl)=O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem