The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Cerebrospinal fluid lymphocytes in experimental allergic encephalomyelitis.》. Authors are Wilkerson, L D; Lisak, R P; Zweiman, B.The article about the compound:1-Iodo-2-methylbutanecas:616-14-8,SMILESS:CCC(CI)C).Application of 616-14-8. Through the article, more information about this compound (cas:616-14-8) is conveyed.
We report characteristics of the cerebrospinal fluid (CSF) pleocytosis (616+/-148 cells/microliter) that occurred in guinea-pigs with definite clinical experimental allergic encephalomyelitis developing 12 to 16 days after sensitization with homologous myelin basic protein. This pleocytosis was not present in the cerebrospinal fluid of a group of animals studied when still healthy, 9 or 10 days after similar sensitization. Eighty-nine per cent of cells in the CSF pleocytosis were small lymphocytes, 8% were larger lymphocytes and the remainder mostly monocytes. Of the lymphocytes, most were E-rosetting or null cells. B-cell markers were uncommon. The cellular patterns in this CSF pleocytosis appear to be similar to those seen in some delayed hypersensitivity responses.
This compound(1-Iodo-2-methylbutane)Application of 616-14-8 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem