Battula, Kumara Swamy published the artcileSynthesis and Biological Evaluation of Novel Thiomorpholine 1,1-Dioxide Derived 1,2,3-Triazole Hybrids as Potential Anticancer Agents, Recommanded Product: tert-Butyl thiomorpholine-4-carboxylate, the main research area is thiomorpholine triazole hybrid preparation antitumor human.
Synthesis and biol. evaluation of a new series of (4-((1-(aryl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)(1,1-dioxidothiomorpholino)methanone derivatives I (R1 = 2-Me, 4-Cl, 2-MeO, etc.) has been described. The synthesized compounds were screened for in vitro anticancer activity against three cancer cell lines (MCF-7, HeLa, and HEK293) and compared with standard drug cisplatin. Among the fourteen derivatives, compounds I (R1 = 2-OMe, 3-OMe, 2-OH) exhibited potent anticancer activity against MCF-7, HeLa, and HEK293. Compounds I (R1 = 2-OMe, 3-OMe) were screened for in vivo studies against EAC bearing mice and found to possess potential anticancer activity.
ChemistrySelect published new progress about Antitumor agents. 220655-09-4 belongs to class thiomorpholine, name is tert-Butyl thiomorpholine-4-carboxylate, and the molecular formula is C9H17NO2S, Recommanded Product: tert-Butyl thiomorpholine-4-carboxylate.
Referemce:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem