Genc, H; Tasdemir, V; Tozlu, I; Ogun, E in [Genc, Hasan; Tozlu, Israfil] Van Yuzuncu Yil Univ, Fac Educ, Dept Sci, TR-65080 Van, Turkey; [Tasdemir, Volkan] Van Yuzuncu Yil Univ, Sci Res & Applicat Ctr, TR-65080 Van, Turkey; [Ogun, Erdal] Van Yuzuncu Yil Univ, Biol Dept, Sci Fac, TR-65080 Van, Turkey published Synthesis of Novel Tetra-Substituted Pyrazole Derivatives from 2,3-Furandione in 2019.0, Cited 42.0. COA of Formula: C7H8N2O. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8.
Synthesis of pyrazole-3-carboxylic acid was progressed via two different protocols, one of which is solid state. Pyrazole-3-carboxylic acid was converted into different derivatives such as ester, urea, amide and nitrile. The amide compound was converted to nitrile using SOCl2 and DMF. Solid state heating of carboxylic acid gave decarboxylated product. Cyclization of tetra-substituted pyrazole with hydrazines resulted in pyrazolopyridazinones. The antimicrobial activities of the synthesized pyrazole derivatives against Bacillus cereus, Escherichia coli, Micrococcus luteus, Staphylococcus aureus, and Saccharomyces cerevisiae were evaluated. One of the pyrazole derivatives which possess nitro group showed antimicrobial activity in only B. cereus, a Gram-positive bacteria, with an MIC of 128 mu g/mL.
About 1-Phenylurea, If you have any questions, you can contact Genc, H; Tasdemir, V; Tozlu, I; Ogun, E or concate me.. COA of Formula: C7H8N2O
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem